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No evidence of major transcriptional changes in the brain of mice exposed to 1800 MHz GSM signal

No Effects Found

Paparini A, Rossi P, Gianfranceschi G, Brugaletta V, Falsaperla R, De Luca P, Romano Spica V. · 2008

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Short-term GSM phone radiation showed no gene expression changes in mouse brains, but longer exposures remain understudied.

Plain English Summary

Summary written for general audiences

Researchers exposed mice to cell phone radiation at 1800 MHz (the frequency used by GSM phones) for one hour to see if it changed gene activity in their brains. Using advanced genetic analysis techniques, they found no significant changes in how genes were expressed in the brain tissue. This suggests that short-term exposure to this type of cell phone radiation at the levels tested does not trigger major changes in brain cell function at the genetic level.

Study Details

To analyze possible effects of microwaves on gene expression, mice were exposed to global system for mobile communication (GSM) 1800 MHz signal for 1 h at a whole body SAR of 1.1 W/kg.

Gene expression was studied in the whole brain, where the average SAR was 0.2 W/kg, by expression mi...

However, when less stringent constraints were adopted to analyze microarray results, 75 genes were f...

Under these specific limited conditions, no consistent indication of gene expression modulation in whole mouse brain was found associated to GSM 1800 MHz exposure.

Cite This Study
Paparini A, Rossi P, Gianfranceschi G, Brugaletta V, Falsaperla R, De Luca P, Romano Spica V. (2008). No evidence of major transcriptional changes in the brain of mice exposed to 1800 MHz GSM signal Bioelectromagnetics. 29(4):312-323, 2008.
Show BibTeX
@article{a_2008_no_evidence_of_major_2792,
  author = {Paparini A and Rossi P and Gianfranceschi G and Brugaletta V and Falsaperla R and De Luca P and Romano Spica V.},
  title = {No evidence of major transcriptional changes in the brain of mice exposed to 1800 MHz GSM signal},
  year = {2008},
  doi = {10.1002/bem.20399},
  url = {https://onlinelibrary.wiley.com/doi/abs/10.1002/bem.20399},
}

Quick Questions About This Study

Researchers exposed mice to cell phone radiation at 1800 MHz (the frequency used by GSM phones) for one hour to see if it changed gene activity in their brains. Using advanced genetic analysis techniques, they found no significant changes in how genes were expressed in the brain tissue. This suggests that short-term exposure to this type of cell phone radiation at the levels tested does not trigger major changes in brain cell function at the genetic level.