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Effect of extremely low frequency magnetic field on antioxidant activity in plasma and red blood cells in spot welders

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Sharifian A, Gharavi M, Pasalar P, Aminian O · 2009

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Magnetic field exposure at occupational levels significantly reduced key antioxidant enzymes by up to 22%, potentially increasing vulnerability to cellular damage.

Plain English Summary

Summary written for general audiences

Researchers studied 46 spot welders exposed to magnetic fields at work versus unexposed workers. Exposed workers showed 22% and 12.3% decreases in key antioxidant enzymes in their blood cells, suggesting magnetic field exposure may weaken the body's natural defenses against cellular damage.

Why This Matters

This study provides compelling evidence that ELF magnetic field exposure can compromise our body's antioxidant defense system, even at exposure levels considered 'safe' by current guidelines. The magnetic field strengths these welders experienced (8.8-84 microTesla) overlap with levels you might encounter near household appliances, power lines, or in certain occupational settings. What makes this research particularly significant is the clear dose-response relationship - the stronger the magnetic field exposure, the greater the reduction in antioxidant enzyme activity. The science demonstrates that oxidative stress is a key mechanism through which EMF exposure may contribute to various health problems. When your body's antioxidant defenses are compromised, you become more vulnerable to cellular damage that can contribute to aging, inflammation, and chronic disease. This adds to a growing body of evidence showing biological effects from EMF exposure occur well below current safety standards.

Exposure Details

Magnetic Field
0.0088 - 0.084 mG
Electric Field
20–133 V/m
Source/Device
50 Hz

Exposure Context

This study used 0.0088 - 0.084 mG for magnetic fields:

This study used 20–133 V/m for electric fields:

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextA logarithmic scale showing exposure levels relative to Building Biology concern thresholds and regulatory limits.Study Exposure Level in ContextThis study: 0.0088 - 0.084 mGExtreme Concern5 mGFCC Limit2,000 mGEffects observed in the No Concern range (Building Biology)FCC limit is 227,273x higher than this exposure level

Study Details

The purpose of this study was to determine a possible relation between exposure to extremely low frequency magnetic field (ELF-MF) and the human antioxidant activity.

The total serum antioxidant status (TAS), red blood cells (RBCs) glutathione peroxidase (GPX) and su...

No significant differences in TAS levels were observed (P value = 0.065). However, in RBCs of expose...

The results of this study indicate that ELF-MF could influence the RBC antioxidant activity and might act as an oxidative stressor. Intracellular antioxidant enzymes such as SOD and GPX were found to be the most important markers involving in this process. The influence of magnetic field on the antioxidant activity of RBCs might occur even at the recommended levels of exposure.

Cite This Study
Sharifian A, Gharavi M, Pasalar P, Aminian O (2009). Effect of extremely low frequency magnetic field on antioxidant activity in plasma and red blood cells in spot welders Int Arch Occup Environ Health. 82(2):259-266, 2009.
Show BibTeX
@article{a_2009_effect_of_extremely_low_460,
  author = {Sharifian A and Gharavi M and Pasalar P and Aminian O},
  title = {Effect of extremely low frequency magnetic field on antioxidant activity in plasma and red blood cells in spot welders},
  year = {2009},
  doi = {10.1007/s00420-008-0332-2},
  url = {https://link.springer.com/article/10.1007/s00420-008-0332-2},
}

Quick Questions About This Study

Researchers studied 46 spot welders exposed to magnetic fields at work versus unexposed workers. Exposed workers showed 22% and 12.3% decreases in key antioxidant enzymes in their blood cells, suggesting magnetic field exposure may weaken the body's natural defenses against cellular damage.