Note: This study found no significant biological effects under its experimental conditions. We include all studies for scientific completeness.
Protein oxidation under extremely low frequency electric field in guinea pigs. Effect of N-acetyl-L-cysteine treatment.
Güler G, Türközer Z, Ozgur E, Tomruk A, Seyhan N, Karasu C · 2009
View Original AbstractHigh-intensity electric field exposure (12 kV/m) didn't cause protein damage in guinea pigs, suggesting everyday power line exposures pose minimal oxidative risk.
Plain English Summary
Researchers exposed guinea pigs to power line frequency electric fields (12 kV/m for 8 hours daily over 7 days) to study protein damage and whether the antioxidant N-acetyl-L-cysteine could protect against it. The study found no significant protein damage from the electric field exposure alone, though it did reduce a protein synthesis marker in the liver. The antioxidant treatment showed some effects on protein markers, suggesting it may have biological activity in this context.
Study Details
In this study, we detected protein carbonyl content (PCO), advanced oxidation protein products (AOPP) in liver and 3-nitrotyrosine (3-NT) levels in plasma of guinea pigs in order to investigate the effects of N-acetyl-L-cysteine (NAC) administration on oxidative protein damage induced by power frequency electric (E) field (50 Hz, 12 kV/m, 7 days/8 h/day).
We also analyzed hepatic hydroxyproline level to study protein synthesis. According to the findings ...
However, liver hydroxyproline level was significantly diminished in the E field exposure group compa...
Show BibTeX
@article{g_2009_protein_oxidation_under_extremely_2845,
author = {Güler G and Türközer Z and Ozgur E and Tomruk A and Seyhan N and Karasu C},
title = {Protein oxidation under extremely low frequency electric field in guinea pigs. Effect of N-acetyl-L-cysteine treatment.},
year = {2009},
url = {https://pubmed.ncbi.nlm.nih.gov/19390136/},
}