A method for recording unit potentials during electroanesthesia
J. Richard Toleikis, Sanford J. Larson, Donald Dallmann, Anthony Sances, Jr. · 1966
The study described a method to record single neuron activity during electroanesthesia in squirrel monkeys using artifact suppression.
Plain English Summary
Three studies were conducted on squirrel monkeys with trephined skulls and Delron chambers mounted over the sensory motor cortex. Unit activity was recorded using 3 molar KCl glass micropettes with a tip diameter of approximately 10 μm. The exposure used 70 Hz rectangular current pulses of 3 ms duration with a DC bias of 2.5 mA. A triaxial electrode configuration and differential microelectrode preamplifier minimized the rectangular artifact pulses in the recordings. The current was capable of inducing marked changes in the unit potential firing rate.
Why This Matters
The animals were immobilized with Flaxidil and maintained on a respirator. The artifact-suppressed signal was subsequently amplified and band-limited between 100 Hz to 10 kHz.
Finding
The current used for this study was capable of inducing marked changes in the unit potential firing rate.
In their words
“The current used for this study was capable of inducing marked changes in the unit potential firing rate.”
Show BibTeX
@article{a_method_for_recording_unit_potentials_during_electroanesthesia_g5771,
author = {J. Richard Toleikis and Sanford J. Larson and Donald Dallmann and Anthony Sances and Jr.},
title = {A method for recording unit potentials during electroanesthesia},
year = {1966},
}