Millimeter wave-induced suppression of B16 F10 melanoma growth in mice: involvement of endogenous opioids.
Radzievsky AA, Gordiienko OV, Szabo I, Alekseev SI, Ziskin MC. · 2004
View Original AbstractMillimeter waves at 61.22 GHz suppressed melanoma growth in mice through the body's natural opioid system, but only with precise timing.
Plain English Summary
Researchers exposed mice with melanoma tumors to millimeter wave radiation at 61.22 GHz for 15 minutes daily over 5 days. They found that this treatment significantly slowed tumor growth, but only when started at a specific time point (day 5 after tumor injection). The anti-cancer effect was blocked when mice were given naloxone, a drug that blocks opioid receptors, suggesting the treatment works by triggering the body's natural opioid system.
Why This Matters
This study presents an intriguing paradox in EMF research. While most studies examine harmful effects of electromagnetic radiation, this controlled experiment found that specific millimeter wave frequencies could actually suppress cancer growth in mice. The power density used (13.3 milliwatts per square centimeter) is significantly higher than typical environmental exposures but within therapeutic ranges used in some medical applications. What makes this particularly noteworthy is the precision required - the timing had to be exact, and the effect disappeared when the body's opioid system was blocked. This suggests that certain EMF frequencies might have therapeutic potential when applied under controlled conditions, though the researchers appropriately caution that extensive safety studies would be needed before human application.
Exposure Details
- Power Density
- 13.3 µW/m²
- Source/Device
- 61.22 GHz
- Exposure Duration
- 15 min
Exposure Context
This study used 13.3 µW/m² for radio frequency:
- 1,330Mx above the Building Biology guideline of 0.1 μW/m²
- 22.2Mx above the BioInitiative Report recommendation of 0.0006 μW/cm²
Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.
Where This Falls on the Concern Scale
Study Details
Millimeter wave treatment (MMWT) is widely used in Eastern European countries, but is virtually unknown in Western medicine. Among reported MMWT effects is suppression of tumor growth. The main aim of the present "blind" and dosimetrically controlled experiments was to evaluate quantitatively the ability of MMWT to influence tumor growth and to assess whether endogenous opioids are involved.
The murine experimental model of B16 F10 melanoma subcutaneous growth was used. MMWT characteristics...
Five daily MMW exposures, if applied starting at the fifth day following B16 melanoma cell injection...
We concluded that MMWT has an anticancer therapeutic potential and that endogenous opioids are involved in MMWT-induced suppression of melanoma growth in mice. However, appropriate indications and contraindications have to be developed experimentally before recommending MMWT for clinical usage.
Show BibTeX
@article{aa_2004_millimeter_waveinduced_suppression_of_1286,
author = {Radzievsky AA and Gordiienko OV and Szabo I and Alekseev SI and Ziskin MC.},
title = {Millimeter wave-induced suppression of B16 F10 melanoma growth in mice: involvement of endogenous opioids.},
year = {2004},
url = {https://pubmed.ncbi.nlm.nih.gov/15300733/},
}