Effects of various extremely low frequency magnetic fields on the free radical processes, natural antioxidant system and respiratory burst system activities in the heart and liver tissues.
Canseven AG, Coskun S, Seyhan N · 2008
View Original AbstractExposure of male guinea pigs to extremely low frequency magnetic fields produced varying changes in free radical and antioxidant markers in heart and liver tissues, depending on field intensity and duration.
Plain English Summary
Researchers exposed guinea pigs to 50 Hz magnetic fields at 1, 2, and 3 mT for 4 h/day and 8 h/day for 5 days, measuring malondialdehyde, nitric oxide, glutathione, and myeloperoxidase activity in heart and liver tissues. MDA levels increased in the liver in some groups but decreased in both liver and heart in group VII. The researchers concluded that field intensity and exposure duration are among the conditions that influence free radical formation and antioxidant enzyme behavior.
Why This Matters
A total of sixty-two male guinea pigs, 10-12 weeks old, were studied in seven groups as control and exposure groups. Controls were kept under the same conditions as the exposed animals but without any magnetic field exposure. NOx levels declined in the heart in some groups and in the liver in others, but increased in the liver in group VII. GSH levels increased in the heart in several groups and in the liver in some groups, but decreased in the liver in other groups. MPO activity decreased in the liver and heart in several groups, but there was a significant increase in MPO activity in the heart in group VII.
Exposure Details
- Magnetic Field
- 1,2 and 3 mT
- Source/Device
- 50 Hz
- Exposure Duration
- 4 h/day and 8 h/day for 5 days
Exposure Context
This study used 1,2 and 3 mT for magnetic fields:
- 50Kx above the Building Biology guideline of 0.2 mG
- 10Kx above the BioInitiative Report recommendation of 1 mG
Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.
Where This Falls on the Concern Scale
Study Details
In the present study, the effects of extremely low frequency (ELF) electromagnetic fields (EMF) were investigated on free radical levels, natural antioxidant systems and respiratory burst system activities in heart and liver tissues of guinea pigs exposed to 50 Hz MFs of 1, 2 and 3 mT for 4 h/day and 8 h/day for 5 days by measuring malondialdehyde (MDA), nitric oxide (NO), glutathione (GSH) levels and myeloperoxidase (MPO) activity.
A total of sixty-two male guinea pigs, 10-12 weeks old were studied in seven groups as control and e...
MDA levels increased in liver in groups II and IV, but decreased in group VII for both liver and he...
From the results, it can be concluded that the intensity and exposure duration of MFs are among the effective conditions on the formation of free radicals and behaviour of antioxidant enzymes.
Show BibTeX
@article{ag_2008_effects_of_various_extremely_328,
author = {Canseven AG and Coskun S and Seyhan N},
title = {Effects of various extremely low frequency magnetic fields on the free radical processes, natural antioxidant system and respiratory burst system activities in the heart and liver tissues.},
year = {2008},
url = {http://nopr.niscair.res.in/handle/123456789/2374},
}