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Assessment of biological changes of continuous whole body exposure to static magnetic field and extremely low frequency electromagnetic fields in mice.

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Hashish AH, El-Missiry MA, Abdelkader HI, Abou-Saleh RH · 2008

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Continuous exposure to power-line frequency EMFs caused weight loss, liver damage, and immune suppression in mice through oxidative stress.

Plain English Summary

Summary written for general audiences

Researchers exposed mice to static magnetic fields and 50 Hz electromagnetic fields (like those from power lines) continuously for 30 days to study health effects. The exposed mice lost weight, showed signs of liver stress including increased oxidative damage, and had significant changes in their blood cells and immune system markers. The study demonstrates that prolonged exposure to these common electromagnetic fields can disrupt normal body functions through oxidative stress.

Why This Matters

This controlled study provides important evidence that continuous exposure to extremely low frequency electromagnetic fields - the type generated by power lines, electrical wiring, and household appliances - can cause measurable biological harm. The 50 Hz frequency tested is exactly what's used in electrical systems across most of the world. What makes this research particularly significant is the comprehensive range of effects observed: weight loss, liver dysfunction, immune system suppression, and cellular oxidative stress. The researchers found these effects occurred through disruption of the body's antioxidant defenses, leading to a cascade of physiological problems. This adds to the growing body of evidence that EMF exposure below current safety guidelines can still trigger biological responses that may compromise health over time.

Exposure Details

Magnetic Field
0.0029 and 1.4 mG
Source/Device
SMF & 50 Hz
Exposure Duration
continuous for 30 days

Exposure Context

This study used 0.0029 and 1.4 mG for magnetic fields:

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextStudy Exposure Level in ContextThis study: 0.0029 and 1.4 mGExtreme Concern - 5 mGFCC Limit - 2,000 mGEffects observed in the No Concern rangeFCC limit is 689,655x higher than this level
A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 50 Hz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 50 HzCell phones~1 GHzWiFi2.4 GHz5G mm28 GHzLogarithmic scale

Study Details

We investigated the effects of continuous whole body exposure to both fields for 30 days on some liver and blood parameters in mice.

Two exposure systems were designed; the first produced a gradient SMF while the second generated uni...

The results showed a gradual body weight loss when mice were exposed to either field. This is couple...

The results indicate that there is a relation between the exposure to SMF or ELF-EMF and the oxidative stress through distressing redox balance leading to physiological disturbances.

Cite This Study
Hashish AH, El-Missiry MA, Abdelkader HI, Abou-Saleh RH (2008). Assessment of biological changes of continuous whole body exposure to static magnetic field and extremely low frequency electromagnetic fields in mice. Ecotoxicol Environ Saf. 71(3):895-902. 2008.
Show BibTeX
@article{ah_2008_assessment_of_biological_changes_384,
  author = {Hashish AH and El-Missiry MA and Abdelkader HI and Abou-Saleh RH},
  title = {Assessment of biological changes of continuous whole body exposure to static magnetic field and extremely low frequency electromagnetic fields in mice.},
  year = {2008},
  
  url = {https://www.sciencedirect.com/science/article/abs/pii/S0147651307002357},
}

Quick Questions About This Study

Yes, this 2008 study found that mice exposed to static magnetic fields for 30 days experienced gradual weight loss along with decreased blood glucose and protein levels. The continuous exposure disrupted normal metabolism and body functions through oxidative stress mechanisms.
Research shows that 30-day exposure to 50 Hz electromagnetic fields significantly increased liver enzyme activity and oxidative damage markers in mice. The study found elevated lactate dehydrogenase and reduced antioxidant levels, indicating liver stress from power line frequency exposure.
A 30-day mouse study revealed that static magnetic field exposure significantly decreased monocyte, platelet, and lymphocyte counts while increasing granulocyte percentages. These blood cell changes suggest immune system disruption from prolonged magnetic field exposure.
Yes, research demonstrates that 30 days of static magnetic field or 50 Hz EMF exposure significantly decreased glutathione levels in liver tissue while increasing lipid peroxidation. This antioxidant depletion indicates cellular oxidative stress from electromagnetic field exposure.
Studies show that continuous magnetic field exposure for 30 days significantly reduced splenic T and B lymphocyte levels in mice. The research indicates that whole body electromagnetic field exposure can suppress immune system function through oxidative stress pathways.