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The effect of electromagnetic field on reactive oxygen species production in human neutrophils in vitro.

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Poniedzialek B, Rzymski P, Nawrocka-Bogusz H, Jaroszyk F, Wiktorowicz K · 2013

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Only EMF tuned to the calcium ion cyclotron resonance frequency affected reactive oxygen species production in human neutrophils, with the effect depending on magnetic induction level.

Plain English Summary

Summary written for general audiences

Researchers investigated the effect of low frequency electromagnetic field on reactive oxygen species production in human neutrophils in peripheral blood in vitro. Three different levels of magnetic induction were analyzed: 10, 40 and 60 μT. Incubation in EMF slightly inhibited activity in unstimulated neutrophils, while activity increased in PMA-stimulated neutrophils after incubation in EMF.

Why This Matters

The study tested several differently generated EMF types to see which, if any, could change how much reactive oxygen species neutrophils produced. Only the EMF tuned to the calcium ion cyclotron resonance frequency produced an effect, and that effect depended on the magnetic induction value used. To measure ROS production, the researchers used two fluorescent dyes and assessed results by flow cytometry. Phorbol 12-myristate 13-acetate, described as a strong stimulator of the respiratory burst, was also used in the experiments.

Exposure Details

Magnetic Field
0.01,0.04, 0.06 mT

Exposure Context

This study used 0.01,0.04, 0.06 mT for magnetic fields:

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextStudy Exposure Level in ContextThis study: 0.01,0.04, 0.06 mTExtreme Concern - 5 mGFCC Limit - 2,000 mGEffects observed in the Extreme Concern range (Building Biology)FCC limit is 20 times higher than this level

Study Details

The present study was undertaken in order to determine the effect of low frequency electromagnetic field (EMF) on reactive oxygen species (ROS) production in human neutrophils in peripheral blood in vitro.

We investigated how differently generated EMF and several levels of magnetic induction affect ROS pr...

The experiments demonstrated that only EMF tuned to the calcium ion cyclotron resonance frequency wa...

Cite This Study
Poniedzialek B, Rzymski P, Nawrocka-Bogusz H, Jaroszyk F, Wiktorowicz K (2013). The effect of electromagnetic field on reactive oxygen species production in human neutrophils in vitro. Electromagn Biol Med. 32(3):333-341, 2013a.
Show BibTeX
@article{b_2013_the_effect_of_electromagnetic_443,
  author = {Poniedzialek B and Rzymski P and Nawrocka-Bogusz H and Jaroszyk F and Wiktorowicz K},
  title = {The effect of electromagnetic field on reactive oxygen species production in human neutrophils in vitro.},
  year = {2013},
  doi = {10.3109/15368378.2012.721845},
  url = {https://www.tandfonline.com/doi/abs/10.3109/15368378.2012.721845},
}
DOI: 10.3109/15368378.2012.721845

Cited By (35 papers)

Quick Questions About This Study

The study examined human neutrophils in peripheral blood, tested in vitro.
Only EMF tuned to the calcium ion cyclotron resonance frequency was able to affect ROS production in neutrophils.
EMF incubation slightly inhibited activity in unstimulated neutrophils, while the activity of PMA-stimulated neutrophils increased after incubation in EMF.
Three levels of magnetic induction were analyzed: 10, 40 and 60 μT.
Statistical analysis showed that the effect depended on the magnetic induction value of the applied EMF.