Investigation of the effects of distance from sources on apoptosis, oxidative stress and cytosolic calcium accumulation via TRPV1 channels induced by mobile phones and Wi-Fi in breast cancer cells.
Çiğ B, Nazıroğlu M. · 2015
View Original AbstractEMF sources within 10 centimeters triggered cellular damage in breast cancer cells, while the same sources beyond 20 centimeters showed no harmful effects.
Plain English Summary
Researchers exposed breast cancer cells to radiation from mobile phones (900 and 1800 MHz) and Wi-Fi (2450 MHz) at various distances to see how proximity affected cellular damage. They found that radiation sources placed within 10 centimeters of the cells triggered harmful effects including oxidative stress, cell death, and calcium overload, while sources placed 20-25 centimeters away showed no significant effects. This suggests that distance from EMF sources matters significantly for cellular protection.
Why This Matters
This study provides important evidence that distance is a critical factor in EMF exposure effects. The finding that harmful cellular responses occurred only when sources were within 10 centimeters demonstrates the inverse square law in action - EMF intensity drops dramatically with distance. What makes this research particularly relevant is that it used frequencies identical to those emitted by our everyday devices: cell phone signals at 900 and 1800 MHz, and Wi-Fi at 2450 MHz. The study's focus on breast cancer cells and the specific biological pathways involved (TRPV1 calcium channels) adds to our understanding of how EMF exposure might influence cancer cell behavior. While this was conducted on isolated cells rather than living tissue, the clear distance-dependent effects align with the precautionary principle that many EMF researchers advocate.
Exposure Information
Specific exposure levels were not quantified in this study. The study examined exposure from: 900, 1800 and 2450 MHz Duration: 1 hour
Study Details
We aimed to investigate the effects of distance from sources on calcium signaling, cytosolic ROS production, cell viability, apoptosis, plus caspase-3 and -9 values induced by mobile phones and Wi-Fi in breast cancer cells MCF-7 human breast cancer cell lines were divided into A, B, C and D groups as control, 900, 1800 and 2450 MHz groups, respectively.
Cells in Group A were used as control and were kept in cell culture conditions without EMR exposure....
The cytosolic ROS production, Ca2+ concentrations, apoptosis, caspase-3 and caspase-9 values were hi...
Show BibTeX
@article{b_2015_investigation_of_the_effects_1986,
author = {Çiğ B and Nazıroğlu M.},
title = {Investigation of the effects of distance from sources on apoptosis, oxidative stress and cytosolic calcium accumulation via TRPV1 channels induced by mobile phones and Wi-Fi in breast cancer cells.},
year = {2015},
url = {https://pubmed.ncbi.nlm.nih.gov/25703814/},
}