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2.45-Gz wireless devices induce oxidative stress and proliferation through cytosolic Ca²⁺ influx in human leukemia cancer cells.

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Nazıroğlu M, Ciğ B, Doğan S, Uğuz AC, Dilek S, Faouzi D. · 2012

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WiFi-frequency radiation promoted cancer cell growth and oxidative stress in lab studies, with effects increasing over time.

Plain English Summary

Summary written for general audiences

Researchers exposed human leukemia cancer cells to 2.45 GHz radiation (the same frequency used by WiFi and microwaves) for periods ranging from 1 to 24 hours. They found that this radiation caused cancer cells to multiply more rapidly and triggered harmful oxidative stress by allowing excess calcium to flood into the cells. The longer the exposure, the more pronounced these effects became.

Why This Matters

This study reveals a concerning mechanism by which everyday wireless radiation may promote cancer cell growth. The 2.45 GHz frequency tested is identical to what your WiFi router, microwave oven, and many Bluetooth devices emit continuously in your home and office. What makes this research particularly significant is that it identifies the specific biological pathway involved - calcium channel disruption leading to oxidative stress and increased cell proliferation. The time-dependent response, with effects growing stronger over 24 hours of exposure, suggests that chronic exposure to these common frequencies could have cumulative impacts on cellular health. While this study used cancer cells in laboratory conditions rather than healthy human tissue, it adds to a growing body of evidence that our wireless devices may be affecting us at the cellular level through well-understood biological mechanisms.

Exposure Information

Specific exposure levels were not quantified in this study. The study examined exposure from: 2.45 GHz Duration: 1, 2, 12 and 24 hours

Study Details

Electromagnetic radiation from wireless devices may affect biological systems by increasing free radicals. The present study was designed to determine the effects of 2.45 GHz radiation on the antioxidant redox system, calcium ion signaling, cell count and viability in human leukemia 60 cells.

Twelve cell cultures were equally divided into two main groups as controls (n = 6) and irradiated (n...

The extent of lipid peroxidation, cytosolic free Ca²⁺ and cell numbers were higher in 2.45 GHz group...

2.45 GHz electromagnetic radiation appears to induce proliferative effects through oxidative stress and Ca²⁺ influx although blocking of transient receptor potential melastatin 2 channels by 2-aminoethyl diphenylborinate seems to counteract the effects on Ca²⁺ ions influx.

Cite This Study
Nazıroğlu M, Ciğ B, Doğan S, Uğuz AC, Dilek S, Faouzi D. (2012). 2.45-Gz wireless devices induce oxidative stress and proliferation through cytosolic Ca²⁺ influx in human leukemia cancer cells. Int J Radiat Biol. 88(6):449-456, 2012.
Show BibTeX
@article{m_2012_245gz_wireless_devices_induce_2465,
  author = {Nazıroğlu M and Ciğ B and Doğan S and Uğuz AC and Dilek S and Faouzi D. },
  title = {2.45-Gz wireless devices induce oxidative stress and proliferation through cytosolic Ca²⁺ influx in human leukemia cancer cells.},
  year = {2012},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/22489926/},
}

Quick Questions About This Study

Researchers exposed human leukemia cancer cells to 2.45 GHz radiation (the same frequency used by WiFi and microwaves) for periods ranging from 1 to 24 hours. They found that this radiation caused cancer cells to multiply more rapidly and triggered harmful oxidative stress by allowing excess calcium to flood into the cells. The longer the exposure, the more pronounced these effects became.