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Focus formation of C3H/10T1/2 cells and exposure to a 836.55 MHz modulated radiofrequency field.

No Effects Found

Cain CD, Thomas DL, Adey WR · 1997

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Cell phone-like radiation did not promote cancer cell formation in this 28-day laboratory study, but longer-term human effects remain uncertain.

Plain English Summary

Summary written for general audiences

Researchers exposed mouse cells to cell phone-like radiation (836.55 MHz TDMA signals) for 28 days to see if it would enhance cancer cell formation when combined with a known tumor-promoting chemical. The radiation exposure at levels similar to cell phone use did not increase cancer cell formation compared to unexposed cells. This suggests that this type of radiofrequency exposure does not act as a tumor promoter in laboratory cell cultures.

Study Details

We have tested the hypothesis that exposures to radiofrequency (RF) fields using a form of digital modulation (TDMA) and a chemical tumor promoter, 12-O-tetradecanoylphorbol-13-acetate (TPA), are copromoters that enhance focus formation of transformed cells in coculture with parental C3H/10T1/2 murine fibroblasts. RF field exposures did not influence TPA's dose-dependent promotion of focus formation in coculture

Cell cultures were exposed to an 836.55 MHz TDMA-modulated field in TEM transmission line chambers, ...

At 1.5 μW/g, TPA-induced focus formation (at 10, 30, and 50 ng/ml) was not significantly different i...

The findings support a conclusion that repeated exposures to this RF field do not influence tumor promotion in vitro, based on the RF field's inability to enhance TPA-induced focus formation.

Cite This Study
Cain CD, Thomas DL, Adey WR (1997). Focus formation of C3H/10T1/2 cells and exposure to a 836.55 MHz modulated radiofrequency field. Bioelectromagnetics 18(3):237-243, 1997.
Show BibTeX
@article{cd_1997_focus_formation_of_c3h10t12_2962,
  author = {Cain CD and Thomas DL and Adey WR},
  title = {Focus formation of C3H/10T1/2 cells and exposure to a 836.55 MHz modulated radiofrequency field.},
  year = {1997},
  
  url = {https://onlinelibrary.wiley.com/doi/abs/10.1002/(SICI)1521-186X(1997)18:3%3C237::AID-BEM6%3E3.0.CO;2-3},
}

Quick Questions About This Study

Researchers exposed mouse cells to cell phone-like radiation (836.55 MHz TDMA signals) for 28 days to see if it would enhance cancer cell formation when combined with a known tumor-promoting chemical. The radiation exposure at levels similar to cell phone use did not increase cancer cell formation compared to unexposed cells. This suggests that this type of radiofrequency exposure does not act as a tumor promoter in laboratory cell cultures.