[Apoptosis of human lung carcinoma cell line GLC-82 induced by high power electromagnetic pulse]
Cao XZ, Zhao ML, Wang DW, Dong B. · 2002
View Original AbstractExtremely high electromagnetic pulses killed 13% of lung cancer cells in lab conditions far beyond everyday exposures.
Plain English Summary
Chinese researchers exposed human lung cancer cells to high-intensity electromagnetic pulses (60,000 volts per meter) and found that the pulses triggered cell death (apoptosis) in up to 13.38% of the cancer cells within 6 hours. The electromagnetic pulses altered key proteins that control cell survival, essentially programming the cancer cells to self-destruct. This research explores whether electromagnetic fields might have therapeutic potential against cancer.
Why This Matters
This study presents an intriguing paradox in EMF research. While most EMF studies focus on potential health risks, this research explores whether extremely high-intensity electromagnetic pulses might actually fight cancer by triggering tumor cell death. The 60,000 volts per meter exposure used here is extraordinarily high - roughly 1,000 times stronger than typical power line fields and far beyond anything you'd encounter from household devices. The researchers found that these intense pulses altered critical cellular proteins (bcl-2 and p53) that control whether cells live or die, effectively reprogramming cancer cells for self-destruction. While this opens fascinating questions about EMF's therapeutic potential, it's crucial to understand that these laboratory conditions bear no resemblance to everyday EMF exposures. The reality is that this study examines EMF as a potential medical tool, not as an environmental health concern.
Exposure Details
- Electric Field
- 60000 V/m
- Exposure Duration
- 0 h, 1 h, and 6 hours
Exposure Context
This study used 60000 V/m for electric fields:
- 200Kx above the Building Biology guideline of 0.3 V/m
Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.
Study Details
This study was designed to evaluate the effect of electromagnetic pulse (EMP) on apoptosis of human lung carcinoma cell line GLC-82, so that to explore and develop therapeutic means for cancer.
The injury changes in GLC-82 cells after irradiated with EMP (electric field intensity was 60 kV/m, ...
EMP could obviously inhibited proliferation and activity of lung carcinoma cell line GLC-82. The abs...
EMP promotes apoptosis of GLC-82 cells. At same time, EMP can down-regulate bcl-2 expression and up-regulate p53 expression in GLC-82 cells. The bcl-2 and the p53 protein may involve the apoptotic process.
Show BibTeX
@article{xz_2002_apoptosis_of_human_lung_892,
author = {Cao XZ and Zhao ML and Wang DW and Dong B.},
title = {[Apoptosis of human lung carcinoma cell line GLC-82 induced by high power electromagnetic pulse]},
year = {2002},
url = {https://pubmed.ncbi.nlm.nih.gov/12508535/},
}