3,138 Studies Reviewed. 77.4% Found Biological Effects. The Evidence is Clear.

Effect of isothermal radiofrequency radiation on cytolytic T lymphocytes.

Bioeffects Seen

Cleary, SF, Du, Z, Cao, G, Liu, LM, McCrady, C · 1996

View Original Abstract
Share:

RF radiation at microwave frequencies directly suppresses immune cell function independent of heating effects, suggesting wireless devices may compromise immunity.

Plain English Summary

Summary written for general audiences

Researchers exposed immune cells called T lymphocytes to 2.45 GHz radiofrequency radiation (the same frequency used in microwave ovens and WiFi) for 24 hours. They found that high-intensity RF exposure significantly reduced the cells' ability to multiply and function properly, while lower intensities caused initial stimulation followed by suppression. The effects were not simply due to heating, suggesting RF radiation directly interferes with immune cell function.

Why This Matters

This study provides compelling evidence that RF radiation can disrupt immune system function at the cellular level. The researchers used 2.45 GHz radiation, the same frequency found in microwave ovens, WiFi routers, and many wireless devices. What makes this research particularly significant is that the scientists ruled out heating effects, demonstrating that RF radiation has direct biological impacts on immune cells beyond just warming tissue. The fact that even lower-intensity exposures caused delayed suppression of immune cell proliferation suggests that our wireless devices may be subtly compromising immune function over time. While the exposure levels in this study were higher than typical consumer device emissions, the dose-dependent response pattern raises important questions about cumulative effects from our increasingly wireless world.

Exposure Details

SAR
25 W/kg
Electric Field
98.4 V/m
Source/Device
2450 MHz
Exposure Duration
24 hours

Exposure Context

This study used 98.4 V/m for electric fields:

This study used 25 W/kg for SAR (device absorption):

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextA logarithmic scale showing exposure levels relative to Building Biology concern thresholds and regulatory limits.Study Exposure Level in ContextThis study: 25 W/kgExtreme Concern0.1 W/kgFCC Limit1.6 W/kgEffects observed in the Extreme Concern range (Building Biology)FCC limit is 0x higher than this exposure level

Study Details

To obtain insight regarding interaction mechanisms, we investigated effects of RF radiation exposure on interleukin 2 (IL-2) -dependent proliferation of cytolytic T lymphocytes (CTLL-2)

After exposure to RF radiation in the presence or absence of IL-2 cells were cultured at various phy...

Exposure to 2450 MHz RIF radiation at specific absorption rates (SARs) of greater than 25 W/kg (indu...

Comparison of the effects of temperature elevation and RF radiation indicated significant qualitative and quantitative differences.

Cite This Study
Cleary, SF, Du, Z, Cao, G, Liu, LM, McCrady, C (1996). Effect of isothermal radiofrequency radiation on cytolytic T lymphocytes. FASEB J 10(8):913-919. 1996.
Show BibTeX
@article{cleary_1996_effect_of_isothermal_radiofrequency_908,
  author = {Cleary and SF and Du and Z and Cao and G and Liu and LM and McCrady and C},
  title = {Effect of isothermal radiofrequency radiation on cytolytic T lymphocytes.},
  year = {1996},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/8666169/},
}

Quick Questions About This Study

Researchers exposed immune cells called T lymphocytes to 2.45 GHz radiofrequency radiation (the same frequency used in microwave ovens and WiFi) for 24 hours. They found that high-intensity RF exposure significantly reduced the cells' ability to multiply and function properly, while lower intensities caused initial stimulation followed by suppression. The effects were not simply due to heating, suggesting RF radiation directly interferes with immune cell function.