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Effects of gamma rays, ultraviolet radiation, sunlight, microwaves and electromagnetic fields on gene expression mediated by human immunodeficiency virus promoter.

No Effects Found

Libertin CR, Panozzo J, Groh KR, Chang-Liu CM, Schreck S, Woloschak GE. · 1994

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Electromagnetic fields showed no effect on HIV gene activation in cells, while microwaves only caused effects through heat generation.

Plain English Summary

Summary written for general audiences

Researchers tested whether different types of radiation and electromagnetic fields could activate HIV gene expression in laboratory cells. They found that only ultraviolet light and microwaves (when they generated excessive heat) could trigger HIV activation, while electromagnetic fields and microwaves at normal temperatures had no effect. This suggests that not all forms of radiation affect viral gene activity in the same way.

Study Details

The aim of this study is to investigate Effects of gamma rays, ultraviolet radiation, sunlight, microwaves and electromagnetic fields on gene expression mediated by human immunodeficiency virus promoter.

Using HeLa cells stably transfected with a construct containing the chloramphenicol acetyl transfera...

These results demonstrated ultraviolet-light-induced transcription from the HIV promoter, as has bee...

These results demonstrate that not all types of radiation and not all DNA-damaging agents are capable of inducing HIV. We hypothesize that induction of HIV transcription may be mediated by several different signals after exposure to radiation.

Cite This Study
Libertin CR, Panozzo J, Groh KR, Chang-Liu CM, Schreck S, Woloschak GE. (1994). Effects of gamma rays, ultraviolet radiation, sunlight, microwaves and electromagnetic fields on gene expression mediated by human immunodeficiency virus promoter. Radiat Res. 140(1):91-96, 1994.
Show BibTeX
@article{cr_1994_effects_of_gamma_rays_3197,
  author = {Libertin CR and Panozzo J and Groh KR and Chang-Liu CM and Schreck S and Woloschak GE.},
  title = {Effects of gamma rays, ultraviolet radiation, sunlight, microwaves and electromagnetic fields on gene expression mediated by human immunodeficiency virus promoter.},
  year = {1994},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/7938460/},
}

Quick Questions About This Study

Researchers tested whether different types of radiation and electromagnetic fields could activate HIV gene expression in laboratory cells. They found that only ultraviolet light and microwaves (when they generated excessive heat) could trigger HIV activation, while electromagnetic fields and microwaves at normal temperatures had no effect. This suggests that not all forms of radiation affect viral gene activity in the same way.