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The Effects of Melatonin on Oxidative Stress Parameters and DNA Fragmentation in Testicular Tissue of Rats Exposed to Microwave Radiation.

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Sokolovic D, Djordjevic B, Kocic G, Stoimenov TJ, Stanojkovic Z, Sokolovic DM, et al. · 2015

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Microwave radiation damaged DNA in rat testicular tissue after just 20 days of 4-hour daily exposure.

Plain English Summary

Summary written for general audiences

Researchers exposed male rats to microwave radiation for 4 hours daily and found it caused oxidative stress and DNA damage in testicular tissue. When rats were also given melatonin (a natural hormone), it significantly protected against these harmful effects, preventing increases in cellular damage markers and reducing DNA fragmentation. This suggests melatonin may help protect reproductive health from microwave radiation exposure.

Why This Matters

This research adds to growing evidence that microwave radiation can damage male reproductive health through oxidative stress mechanisms. The study demonstrates that 4 hours of daily microwave exposure causes measurable DNA fragmentation in testicular tissue within just 20 days. What makes this particularly relevant is that many people now carry microwave-emitting devices like smartphones close to their bodies for extended periods. The protective effects of melatonin are encouraging, but the real takeaway is prevention. The science demonstrates that microwave radiation can harm reproductive cells at the DNA level. Rather than relying on supplements to counteract damage, the smarter approach is reducing your exposure in the first place by keeping devices away from your body and using speakerphone or wired headsets.

Exposure Information

Specific exposure levels were not quantified in this study. Duration: 4 h/day

Study Details

The aim of the study was to evaluate the effect of melatonin treatment on oxidative stress parameters and DNA fragmentation in the testicular tissue of rats exposed to microwave radiation (4 h/day).

Adult Wistar rats were divided in 4 groups: I--treated with saline; II--treated with melatonin; III-...

Melatonin treatment prevented previously registered increases in malondialdehyde after only 20 days...

Melatonin exerts potent antioxidant effects in the testes of rats exposed to microwaves by decreasing the intensity of oxidative stress; it also reduces DNA fragmentation.

Cite This Study
Sokolovic D, Djordjevic B, Kocic G, Stoimenov TJ, Stanojkovic Z, Sokolovic DM, et al. (2015). The Effects of Melatonin on Oxidative Stress Parameters and DNA Fragmentation in Testicular Tissue of Rats Exposed to Microwave Radiation. Adv Clin Exp Med. 24(3):429-436, 2015.
Show BibTeX
@article{d_2015_the_effects_of_melatonin_2609,
  author = {Sokolovic D and Djordjevic B and Kocic G and Stoimenov TJ and Stanojkovic Z and Sokolovic DM and et al. },
  title = {The Effects of Melatonin on Oxidative Stress Parameters and DNA Fragmentation in Testicular Tissue of Rats Exposed to Microwave Radiation.},
  year = {2015},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/26467130/},
}

Quick Questions About This Study

Researchers exposed male rats to microwave radiation for 4 hours daily and found it caused oxidative stress and DNA damage in testicular tissue. When rats were also given melatonin (a natural hormone), it significantly protected against these harmful effects, preventing increases in cellular damage markers and reducing DNA fragmentation. This suggests melatonin may help protect reproductive health from microwave radiation exposure.