The developmental effects of extremely low frequency electric fields on visual and somatosensory evoked potentials in adult rats
Gok DK, Akpinar D, Hidisoglu E, Ozen S, Agar A, Yargicoglu P. · 2016
View Original AbstractRats developmentally exposed to extremely low frequency electric fields showed delayed evoked potential latencies and elevated markers of lipid peroxidation.
Plain English Summary
Researchers divided Wistar albino female rats into four groups: a control group, a prenatal-exposure group, a postnatal-exposure group, and a combined prenatal-plus-postnatal-exposure group. Pregnant rats in the prenatal and combined groups were exposed to a 50 Hz electric field at 12 kV/m for 1 hour per day during pregnancy, while postnatal animals were exposed for 68 days after birth. The latencies of visual evoked potential components were significantly prolonged in all exposed groups compared with controls. Retina TBARS levels, a marker of lipid peroxidation, were significantly elevated in all experimental groups compared with controls.
Why This Matters
For somatosensory evoked potentials, all components were delayed in the combined-exposure group, while only certain components were delayed in the prenatal-only and postnatal-only groups. Brain TBARS levels were significantly increased in the prenatal-only and postnatal-only groups. The researchers suggested that the changes seen in evoked potentials could at least partly be explained by lipid peroxidation in the retina and brain.
Exposure Details
- Electric Field
- 12000 V/m
- Source/Device
- 50 Hz
- Exposure Duration
- 1 h/day
Exposure Context
This study used 12000 V/m for electric fields:
- 40Kx above the Building Biology guideline of 0.3 V/m
Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.
Study Details
The purpose of our study was to investigate the developmental effects of extremely low frequency electric fields (ELF-EFs) on visual evoked potentials (VEPs) and somatosensory-evoked potentials (SEPs) and to examine the relationship between lipid peroxidation and changes of these potentials.
In this context, thiobarbituric acid reactive substances (TBARS) levels were determined as an indica...
The latencies of VEP components in all experimental groups were significantly prolonged versus C gro...
In conclusion, alterations seen in evoked potentials, at least partly, could be explained by lipid peroxidation in the retina and brain.
Show BibTeX
@article{dk_2016_the_developmental_effects_of_378,
author = {Gok DK and Akpinar D and Hidisoglu E and Ozen S and Agar A and Yargicoglu P.},
title = {The developmental effects of extremely low frequency electric fields on visual and somatosensory evoked potentials in adult rats},
year = {2016},
doi = {10.3109/15368378.2014.987923},
url = {https://www.tandfonline.com/doi/abs/10.3109/15368378.2014.987923?journalCode=iebm20},
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