Effect of an acute 900 MHz GSM exposure on glia in the rat brain: A time-dependent study
Brillaud E, Piotrowski A, de Seze R · 2007
View Original AbstractA single 900 MHz GSM exposure produced a temporary increase in glial reactivity in rat brain regions, peaking 2 days after exposure.
Plain English Summary
Researchers measured GFAP expression in rat brains 2, 3, 6, and 10 days after a single 15-minute 900 MHz GSM exposure at a brain averaged SAR of 6 W/kg. A statistically significant increase in GFAP stained surface area was observed 2 days after exposure in the frontal cortex and the caudate putamen. A smaller statistically significant increase was noted 3 days after exposure in those same areas and in the cerebellum cortex. The researchers concluded this was a temporary effect, probably due to a hypertrophy of glial cells, and noted that whether the effect could be harmful remains to be studied.
Why This Matters
GFAP expression was measured to evaluate glial evolution 2, 3, 6 and 10 days after a single GSM exposure, allowing the researchers to observe how the effect evolved over time. The effect was not uniform across the brain: it appeared first in the frontal cortex and caudate putamen, and only at the 3-day point was it also seen in the cerebellum cortex. The researchers described the result as showing a temporal and a spatial modulation of the effect, suggesting it varied both by location and by time after exposure. These findings were said to confirm an earlier study showing glial reactivity after a 15-minute GSM acute exposure at a brain averaged SAR of 6 W/kg.
Exposure Details
- SAR
- 6 W/kg
- Source/Device
- 900 MHz GSM
- Exposure Duration
- 15 min
Exposure Context
This study used 6 W/kg for SAR (device absorption):
- 15x above the Building Biology guideline of 0.4 W/kg
Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.
Where This Falls on the Concern Scale
Study Details
To study the effect of an acute 900 MHz GSM exposure on glia in the rat brain
In this work we measured GFAP expression, to evaluate glial evolution 2, 3, 6 and 10 days after a si...
A statistically significant increase of GFAP stained surface area was observed 2 days after exposur...
We conclude to a temporary effect, probably due to a hypertrophy of glial cells, with a temporal and a spatial modulation of the effect. Whether this effect could be harmful remains to be studied
Show BibTeX
@article{e_2007_effect_of_an_acute_73,
author = {Brillaud E and Piotrowski A and de Seze R},
title = {Effect of an acute 900 MHz GSM exposure on glia in the rat brain: A time-dependent study},
year = {2007},
url = {https://www.sciencedirect.com/science/article/abs/pii/S0300483X07002983},
}