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Effect of an acute 900 MHz GSM exposure on glia in the rat brain: A time-dependent study

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Brillaud E, Piotrowski A, de Seze R · 2007

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Just 15 minutes of cell phone radiation triggered brain inflammation in rats that lasted over a week, raising questions about daily phone use.

Plain English Summary

Summary written for general audiences

French researchers exposed rats to 15 minutes of cell phone radiation and found brain inflammation that peaked after 2 days and lasted up to 10 days. The study measured stress proteins in brain tissue, suggesting brief phone exposure can trigger inflammatory responses in the brain.

Why This Matters

This study adds to a growing body of evidence showing that radiofrequency radiation affects brain tissue in ways that extend well beyond heating. The 6 W/kg SAR level used here is higher than typical cell phone use (which ranges from 0.5-2 W/kg), but the key finding is that brain inflammation occurred and persisted for over a week after just 15 minutes of exposure. The increase in GFAP indicates glial activation, which is the brain's response to injury or stress. What makes this research particularly significant is that it confirms earlier findings and demonstrates both temporal and spatial patterns in the brain's response. While the researchers appropriately note that whether this effect is harmful requires further study, chronic inflammation in any organ system raises legitimate health concerns. The reality is that most of us carry devices capable of producing similar exposures against our heads for far longer than 15 minutes daily.

Exposure Details

SAR
6 W/kg
Source/Device
900 MHz GSM
Exposure Duration
15 min

Exposure Context

This study used 6 W/kg for SAR (device absorption):

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextA logarithmic scale showing exposure levels relative to Building Biology concern thresholds and regulatory limits.Study Exposure Level in ContextThis study: 6 W/kgExtreme Concern0.1 W/kgFCC Limit1.6 W/kgEffects observed in the Extreme Concern range (Building Biology)FCC limit is 0x higher than this exposure level

Study Details

To study the effect of an acute 900 MHz GSM exposure on glia in the rat brain

In this work we measured GFAP expression, to evaluate glial evolution 2, 3, 6 and 10 days after a si...

A statistically significant increase of GFAP stained surface area was observed 2 days after exposur...

We conclude to a temporary effect, probably due to a hypertrophy of glial cells, with a temporal and a spatial modulation of the effect. Whether this effect could be harmful remains to be studied

Cite This Study
Brillaud E, Piotrowski A, de Seze R (2007). Effect of an acute 900 MHz GSM exposure on glia in the rat brain: A time-dependent study Toxicology. 238(1):23-33, 2007.
Show BibTeX
@article{e_2007_effect_of_an_acute_73,
  author = {Brillaud E and Piotrowski A and de Seze R},
  title = {Effect of an acute 900 MHz GSM exposure on glia in the rat brain: A time-dependent study},
  year = {2007},
  
  url = {https://www.sciencedirect.com/science/article/abs/pii/S0300483X07002983},
}

Quick Questions About This Study

French researchers exposed rats to 15 minutes of cell phone radiation and found brain inflammation that peaked after 2 days and lasted up to 10 days. The study measured stress proteins in brain tissue, suggesting brief phone exposure can trigger inflammatory responses in the brain.