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Continuous exposure to 900MHz GSM-modulated EMF alters morphological maturation of neural cells.

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Del Vecchio G, Giuliani A, Fernandez M, Mesirca P, Bersani F, Pinto R, Ardoino L, Lovisolo GA, Giardino L, Calzà L · 2009

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Cell phone radiation at legal exposure levels disrupted brain cell development, reducing the growth of neural connections by measurable amounts.

Plain English Summary

Summary written for general audiences

Italian researchers exposed developing brain cells to cell phone radiation at levels similar to what phones emit (1 W/kg SAR at 900 MHz). They found that this radiation significantly reduced the growth of neurites - the branch-like extensions that neurons use to connect and communicate with each other. This suggests that cell phone radiation may interfere with normal brain cell development and connection formation.

Why This Matters

This research addresses a critical question: can cell phone radiation interfere with normal brain development? The findings are particularly concerning because the study used exposure levels (1 W/kg SAR) that are well within current safety limits and similar to what your phone produces during calls. The researchers found measurable disruption to neurite development - the very process by which brain cells form the connections essential for proper neural function. What makes this study especially relevant is that it examined two different types of brain cells and found consistent effects in both, strengthening the reliability of the results. The evidence shows that RF-EMF exposure doesn't just heat tissue - it appears to interfere with fundamental cellular processes that govern how our neurons develop and connect.

Exposure Details

SAR
1 W/kg
Source/Device
900 MHz GSM
Exposure Duration
48 and 72 h (24 and 48 h of SN56 cell line differentiation) or at 24, 72, 120 h (2, 4 and 6 days in vitro for cortical neurons)

Exposure Context

This study used 1 W/kg for SAR (device absorption):

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextA logarithmic scale showing exposure levels relative to Building Biology concern thresholds and regulatory limits.Study Exposure Level in ContextThis study: 1 W/kgExtreme Concern0.1 W/kgFCC Limit1.6 W/kgEffects observed in the Extreme Concern range (Building Biology)FCC limit is 2x higher than this exposure level

Study Details

The effects of radiofrequency electromagnetic field (RF-EMF) exposure on neuronal phenotype maturation have been studied in two different in vitro models: murine SN56 cholinergic cell line and rat primary cortical neurons.

The samples were exposed at a dose of 1 W/kg at 900 MHz GSM modulated. The phenotype analysis was ca...

We found that RF-EMF exposure reduced the number of neurites generated by both cell systems, and thi...

Cite This Study
Del Vecchio G, Giuliani A, Fernandez M, Mesirca P, Bersani F, Pinto R, Ardoino L, Lovisolo GA, Giardino L, Calzà L (2009). Continuous exposure to 900MHz GSM-modulated EMF alters morphological maturation of neural cells. Neurosci Lett. 455(3):173-177, 2009.
Show BibTeX
@article{g_2009_continuous_exposure_to_900mhz_13,
  author = {Del Vecchio G and Giuliani A and Fernandez M and Mesirca P and Bersani F and Pinto R and Ardoino L and Lovisolo GA and Giardino L and Calzà L},
  title = {Continuous exposure to 900MHz GSM-modulated EMF alters morphological maturation of neural cells.},
  year = {2009},
  
  url = {http://www.sciencedirect.com/science/article/pii/S0304394009003632},
}

Quick Questions About This Study

Italian researchers exposed developing brain cells to cell phone radiation at levels similar to what phones emit (1 W/kg SAR at 900 MHz). They found that this radiation significantly reduced the growth of neurites - the branch-like extensions that neurons use to connect and communicate with each other. This suggests that cell phone radiation may interfere with normal brain cell development and connection formation.