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Effect of extremely low frequency magnetic field on glutathione in rat muscles.

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Ciejka E, Jakubowska E, Zelechowska P, Huk-Kolega H, Kowalczyk A, Goraca A · 2014

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Exposure to a 40 Hz, 7 mT magnetic field significantly increased total glutathione levels in rat skeletal muscle.

Plain English Summary

Summary written for general audiences

Researchers studied how an extremely low frequency magnetic field used in magnetotherapy affected glutathione levels and redox state in rat skeletal muscle. Male rats weighing 280-300 g were randomly divided into 3 experimental groups: a control group and treatment groups exposed to 40 Hz, 7 mT for either 0.5 h/day or 1 h/day for 14 days. Both 30 min/day and 60 min/day exposures significantly increased total glutathione levels in skeletal muscle compared to controls (p < 0.001).

Why This Matters

Total glutathione, both oxidized and reduced forms, and the redox state were measured in muscle tissue immediately after the last exposure. The researchers concluded that the duration of exposure played a role in the effects observed. Control rats were kept in a separate room and were not exposed to the magnetic field.

Exposure Details

Magnetic Field
7 mT
Source/Device
40 Hz
Exposure Duration
0.5 h/day for 14 days & 1 h/day for 14 days

Exposure Context

This study used 7 mT for magnetic fields:

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextStudy Exposure Level in ContextThis study: 7 mTExtreme Concern - 5 mGFCC Limit - 2,000 mGEffects observed in the Extreme Concern range (Building Biology)This level is 35 times the FCC limit
A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 40 Hz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 40 HzCell phones~1 GHzWiFi2.4 GHz5G mm28 GHzLogarithmic scale

Study Details

The aim of the presented study was to evaluate the effect of extremely low frequency magnetic field used in the magnetotherapy on the level of total glutathione, oxidized and reduced, and the redox state of the skeletal muscle cells, depending on the duration of exposure to magnetic field.

The male rats, weight of 280-300 g, were randomly devided into 3 experimental groups: controls (grou...

Exposure to low magnetic field: 40 Hz, 7 mT for 30 min/day and 60 min/day for 2 weeks significantly ...

Exposure to magnetic fields used in the magnetic therapy plays an important role in the development of adaptive mechanisms responsible for maintaining the oxidation-reduction balance in the body and depends on exposure duration.

Cite This Study
Ciejka E, Jakubowska E, Zelechowska P, Huk-Kolega H, Kowalczyk A, Goraca A (2014). Effect of extremely low frequency magnetic field on glutathione in rat muscles. Med Pr. 65(3):343-349, 2014.
Show BibTeX
@article{e_2014_effect_of_extremely_low_338,
  author = {Ciejka E and Jakubowska E and Zelechowska P and Huk-Kolega H and Kowalczyk A and Goraca A},
  title = {Effect of extremely low frequency magnetic field on glutathione in rat muscles.},
  year = {2014},
  
  url = {https://europepmc.org/article/med/25230563},
}
PubMed: 25230563

Cited By (8 papers)

Quick Questions About This Study

The study used an extremely low frequency magnetic field at 40 Hz and 7 mT, the type used in magnetotherapy.
Exposure at 40 Hz and 7 mT for both 30 min/day and 60 min/day for 2 weeks significantly increased total glutathione levels in skeletal muscle compared to the control group (p < 0.001).
The researchers found that effects depended on exposure duration, suggesting it plays an important role in maintaining the oxidation-reduction balance.
Male rats weighing 280-300 g were randomly divided into 3 experimental groups, with treatment groups exposed to 40 Hz, 7 mT for either 0.5 h/day or 1 h/day for 14 days.
Muscle samples were taken immediately after the last exposure, while rats were under pentobarbital anesthesia.