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Effects of mobile phone use on brain tissue from the rat and a possible protective role of vitamin C - a preliminary study.

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Imge EB, Kiliçoğlu B, Devrim E, Cetin R, Durak I · 2010

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Mobile phone use inhibited 5'-NT and CAT activities in rat brain tissue, and researchers suggested vitamin C may play a protective role against these effects.

Plain English Summary

Summary written for general audiences

Forty female rats were divided into four groups: control, mobile phone, mobile phone plus vitamin C, and vitamin C alone. The mobile phone groups were exposed to a mobile phone signal (900 MHz), and vitamin C was administered orally for four weeks. Mobile phone exposure caused an inhibition in 5'-NT and CAT activities compared to the control group, while GSH-Px activity and MDA levels were reduced but not significantly. The researchers suggested that vitamin C may play a protective role against detrimental effects of mobile phone radiation in brain tissue.

Why This Matters

Researchers analyzed brain tissue for several markers, including malondialdehyde, antioxidant potential, superoxide dismutase, catalase, glutathione peroxidase, xanthine oxidase, adenosine deaminase, and 5'-nucleotidase. Reductions in GSH-Px activity and MDA levels in the mobile phone group did not reach significance. Vitamin C caused a significant increase in GSH-Px activity and a non-significant increase in 5'-NT, ADA, and CAT enzyme activities.

Exposure Details

SAR
0.95 W/kg
Source/Device
900 MHz Mobie phone
Exposure Duration
4 weeks - mobile phone in stand-by mode, four calls a day for 10 minutes.

Exposure Context

This study used 0.95 W/kg for SAR (device absorption):

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextStudy Exposure Level in ContextThis study: 0.95 W/kgExtreme Concern - 0.1 W/kgFCC Limit - 1.6 W/kgEffects observed in the Extreme Concern range (Building Biology)FCC limit is 2 times higher than this level
A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 900 MHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 900 MHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

Study Details

To evaluate effects of mobile phone use on brain tissue and a possible protective role of vitamin C.

Forty female rats were divided into four groups randomly (Control, mobile phone, mobile phone plus v...

Mobile phone use caused an inhibition in 5'-NT and CAT activities as compared to the control group. ...

Our results suggest that vitamin C may play a protective role against detrimental effects of mobile phone radiation in brain tissue.

Cite This Study
Imge EB, Kiliçoğlu B, Devrim E, Cetin R, Durak I (2010). Effects of mobile phone use on brain tissue from the rat and a possible protective role of vitamin C - a preliminary study. Int J Radiat Biol. 86(12):1044-1049, 2010.
Show BibTeX
@article{eb_2010_effects_of_mobile_phone_110,
  author = {Imge EB and Kiliçoğlu B and Devrim E and Cetin R and Durak I},
  title = {Effects of mobile phone use on brain tissue from the rat and a possible protective role of vitamin C - a preliminary study.},
  year = {2010},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/20698742/},
}

Cited By (31 papers)

Quick Questions About This Study

The mobile phone group was exposed to a mobile phone signal (900 MHz).
Mobile phone use caused an inhibition in 5'-NT and CAT activities compared to the control group.
Vitamin C caused a significant increase in the activity of GSH-Px.
The researchers suggested that vitamin C may play a protective role against detrimental effects of mobile phone radiation in brain tissue.
Forty female rats were divided into four groups: control, mobile phone, mobile phone plus vitamin C, and vitamin C alone.