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Effects of electromagnetic radiation on spatial memory and synapses in rat hippocampal CA1.

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Li Y, Shi C, Lu G, Xu Q, Liu S. · 2012

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Mobile phone radiation at typical exposure levels damaged rats' memory centers and impaired spatial learning after just one month of daily exposure.

Plain English Summary

Summary written for general audiences

Researchers exposed rats to cell phone radiation (900 MHz) for two hours daily over one month. The exposed rats showed worse spatial memory in maze tests and had damaged brain cells with fewer neural connections in the hippocampus, suggesting regular phone radiation may impair memory formation.

Why This Matters

This study provides compelling evidence that mobile phone radiation can cause measurable damage to the brain's memory centers. The SAR levels used (0.52-1.08 W/kg) fall within the range of typical cell phone exposures, making these findings directly relevant to everyday device use. What makes this research particularly significant is that it demonstrates both functional impairment (worse spatial memory) and the underlying physical damage (fewer synapses, damaged mitochondria) that could explain it. The hippocampus is crucial for forming new memories and spatial navigation, so damage to this region could have real-world consequences for learning and memory formation. While this is animal research, the consistency of these findings with other studies showing cognitive effects from RF radiation strengthens the case that our current safety standards may not adequately protect brain function.

Exposure Details

SAR
0.52–1.08 W/kg
Source/Device
900 MHz
Exposure Duration
2 hours every day over 1 month

Exposure Context

This study used 0.52–1.08 W/kg for SAR (device absorption):

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextA logarithmic scale showing exposure levels relative to Building Biology concern thresholds and regulatory limits.Study Exposure Level in ContextThis study: 0.52–1.08 W/kgExtreme Concern0.1 W/kgFCC Limit1.6 W/kgEffects observed in the Extreme Concern range (Building Biology)FCC limit is 3x higher than this exposure level

Study Details

In this study, we investigated the effects of mobile phone radiation on spatial learning, reference memory, and morphology in related brain regions.

After the near-field radiation (0.52–1.08 W/kg) was delivered to 8-week-old Wistar rats 2 hours per ...

The morphological changes included mitochondrial degenerations, fewer synapses, and shorter postsyna...

Cite This Study
Li Y, Shi C, Lu G, Xu Q, Liu S. (2012). Effects of electromagnetic radiation on spatial memory and synapses in rat hippocampal CA1. Neural Regen Res. 7(16):1248-1255, 2012.
Show BibTeX
@article{y_2012_effects_of_electromagnetic_radiation_125,
  author = {Li Y and Shi C and Lu G and Xu Q and Liu S. },
  title = {Effects of electromagnetic radiation on spatial memory and synapses in rat hippocampal CA1.},
  year = {2012},
  
  url = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336960/},
}

Quick Questions About This Study

Researchers exposed rats to cell phone radiation (900 MHz) for two hours daily over one month. The exposed rats showed worse spatial memory in maze tests and had damaged brain cells with fewer neural connections in the hippocampus, suggesting regular phone radiation may impair memory formation.