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Effect of 900MHz electromagnetic fields on energy metabolism of cerebral cortical neurons in postnatal rat

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Authors not listed · 2004

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Low-intensity 900MHz continuous microwave EMF at 9mW/cm2 (SAR = 3.22mW/g) for 2 hours per day over 4 or 5 consecutive days or 12 hours at a time significantly decreased cytochrome oxidase activity in postnatal rat cerebral cortical neurons (P < 0.001).

Plain English Summary

Summary written for general audiences

Researchers exposed cerebral cortical neurons from postnatal rats to low-intensity 900MHz continuous microwave electromagnetic fields at 9mW/cm2 with a SAR of 3.22mW/g for 2 hours per day over 4 or 5 consecutive days and also for 12 hours at a time. They measured cytochrome oxidase activity as a marker of energy metabolism. Compared to sham-exposed neurons, cytochrome oxidase activity decreased significantly in neurons exposed for 2 hours per day and in those exposed for 12 hours (P < 0.001).

Why This Matters

The authors classified the down-regulation of cytochrome oxidase as a non-thermal effect. They observed a cumulative power effect in the neuronal response to the microwave. The effect on cytochrome oxidase could be recovered to some extent. The effect did not closely relate to the age of the neurons at first exposure.

Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 900 MHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 900 MHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

Specific exposure levels were not quantified in this study.

Cite This Study
Unknown (2004). Effect of 900MHz electromagnetic fields on energy metabolism of cerebral cortical neurons in postnatal rat.
Show BibTeX
@article{effect_of_900mhz_electromagnetic_fields_on_energy_metabolism_of_cerebral_cortical_neurons_in_postnatal_rat_ce1039,
  author = {Unknown},
  title = {Effect of 900MHz electromagnetic fields on energy metabolism of cerebral cortical neurons in postnatal rat},
  year = {2004},
  
  
}

Quick Questions About This Study

Neurons were exposed to low intensity 900MHz continuous microwave EMF at 9mW/cm2 with a SAR of 3.22mW/g for 2 hours per day over 4 or 5 consecutive days and for 12 hours at a time.
The authors measured cytochrome oxidase activity as the biological endpoint.
Cytochrome oxidase activity decreased significantly in neurons exposed for 2 hours per day and in those exposed for 12 hours compared to sham-exposed neurons (P < 0.001).
They classified the down-regulation of cytochrome oxidase as a non-thermal effect and noted a cumulative power effect in the neuronal response.
The influence on cytochrome oxidase could be recovered to some extent.