Exposure to Radiofrequency Induces Synaptic Dysfunction in Cortical Neurons Causing Learning and Memory Alteration in Early Postnatal Mice
Authors not listed · 2024
Researchers exposed postnatal day 28 mice to 1850 MHz RF-EMF at 4.0 W/kg daily for 4 weeks and found reduced mushroom-shaped dendritic spines in the prefrontal cortex and altered spatial learning and memory.
Plain English Summary
The study investigated the effects of 1850 MHz RF-EMF exposure at a specific absorption rate of 4.0 W/kg on cortical neurons in mice at postnatal day 28. Daily exposure for 4 weeks significantly reduced the number of mushroom-shaped dendritic spines in the prefrontal cortex. Prolonged exposure over 9 days gradually decreased postsynaptic density 95 puncta and inhibited neurite outgrowth in developing cortical neurons. Expression levels of genes associated with synapse formation, such as synaptic cell adhesion molecules and cyclin-dependent kinase 5, were reduced in the cerebral cortexes of exposed mice. Behavioral assessments using the Morris water maze revealed altered spatial learning and memory after the 4-week exposure period.
Why This Matters
The researchers noted that widespread wireless device use has made RF-EMF exposure unavoidable, particularly for children. They concluded that RF-EMF exposure during childhood may disrupt synaptic function in the cerebral cortex and affect nervous system development.
Exposure Information
Specific exposure levels were not quantified in this study.
Show BibTeX
@article{exposure_to_radiofrequency_induces_synaptic_dysfunction_in_cortical_neurons_causing_learning_and_memory_alteration_in_early_postnatal_mice_ce2861,
author = {Unknown},
title = {Exposure to Radiofrequency Induces Synaptic Dysfunction in Cortical Neurons Causing Learning and Memory Alteration in Early Postnatal Mice},
year = {2024},
doi = {10.3390/ijms25168589},
}