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Exposure to an 890-MHz mobile phone-like signal and serum levels of S100B and transthyretin in volunteers

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Söderqvist F, Carlberg M, Hansson Mild K, Hardell L · 2009

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Exposure to a GSM 890 MHz signal did not significantly raise S100B levels, but transthyretin showed a statistically significant increase at 60 min after exposure ended.

Plain English Summary

Summary written for general audiences

Researchers exposed 41 volunteers to a 30 min GSM 890 MHz signal at an average specific energy absorption rate distribution of 1.0 W/kg in the temporal area of the head. S100B showed no statistically significant increase, while transthyretin showed a statistically significant increase in the final blood sample 60 min after the end of the provocation compared to the sample taken immediately after provocation (p = 0.02). The researchers noted that the clinical significance of this finding, if any, is unknown.

Why This Matters

The study aimed to test whether exposure to a mobile phone-like signal alters the integrity of the human blood-brain and blood-cerebrospinal fluid barriers. Blood samples were taken repeatedly before and after the provocation to track any changes in serum marker levels. The transthyretin increase was observed specifically when comparing the final sample, taken 60 min after the end of the provocation, to the sample taken immediately after provocation. The researchers called for further randomized studies with use of additional more brain specific markers.

Exposure Details

SAR
1 W/kg
Source/Device
GSM 890 MHz
Exposure Duration
30 min

Exposure Context

This study used 1 W/kg for SAR (device absorption):

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextStudy Exposure Level in ContextThis study: 1 W/kgExtreme Concern - 0.1 W/kgFCC Limit - 1.6 W/kgEffects observed in the Extreme Concern range (Building Biology)FCC limit is 2 times higher than this level
A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 890 MHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 890 MHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

Study Details

The aim of this study was to test, using peripheral markers, whether exposure to a mobile phone-like signal alters the integrity of the human blood-brain and blood-cerebrospinal fluid barriers.

A provocation study was carried out that exposed 41 volunteers to a 30 min GSM 890 MHz signal with a...

Repeated blood sampling before and after the provocation showed no statistically significant increa...

The clinical significance of this finding, if any, is unknown. Further randomized studies with use of additional more brain specific markers are needed.

Cite This Study
Söderqvist F, Carlberg M, Hansson Mild K, Hardell L (2009). Exposure to an 890-MHz mobile phone-like signal and serum levels of S100B and transthyretin in volunteers Toxicol Lett. 189(1):63-66, 2009.
Show BibTeX
@article{f_2009_exposure_to_an_890mhz_187,
  author = {Söderqvist F and Carlberg M and Hansson Mild K and Hardell L},
  title = {Exposure to an 890-MHz mobile phone-like signal and serum levels of S100B and transthyretin in volunteers},
  year = {2009},
  
  url = {https://www.sciencedirect.com/science/article/abs/pii/S037842740900246X},
}

Quick Questions About This Study

41 volunteers were exposed to a 30 min GSM 890 MHz signal at an average specific energy absorption rate distribution of 1.0 W/kg in the temporal area of the head.
There was no statistically significant increase in serum levels of S100B after the provocation.
A statistically significant increase in transthyretin was seen in the final blood sample 60 min after the end of the provocation compared to the sample taken immediately after provocation (p = 0.02).
The researchers stated that the clinical significance of this finding, if any, is unknown.
They called for further randomized studies with use of additional more brain specific markers.