Radioprotective effects of honeybee venom (Apismellifera) against 915-MHz microwave radiation-induced DNA damage in wistar rat lymphocytes: in vitro study.
Gajski G, Garaj-Vrhovac V. · 2009
View Original AbstractBee venom showed a radioprotective effect against DNA damage in rat lymphocytes exposed to 915-MHz microwave radiation.
Plain English Summary
Researchers investigated whether bee venom could protect against DNA damage caused by 915-MHz microwave radiation in Wistar rat lymphocytes. Whole blood lymphocytes were treated with 1 μg/mL bee venom before irradiation, and comet assays were used to assess basal and oxidative DNA damage. Bee venom showed a decrease in DNA damage compared with irradiated samples, and was found to have a radioprotective effect against both basal and oxidative DNA damage.
Why This Matters
Lymphocytes were treated with 1 μg/mL bee venom 4 hours prior to and immediately before irradiation. The Fpg-modified comet assay parameters were statistically different from controls, suggesting that oxidative stress is a possible mechanism of DNA damage induction. At the low concentrations used, bee venom was not genotoxic and did not produce oxidative damage on its own.
Exposure Details
- SAR
- 0.6 W/kg
- Power Density
- 0.24 mW/cm²
- Electric Field
- 30 V/m
- Source/Device
- 915-MHz
- Exposure Duration
- 30 minutes
Exposure Context
This study used 0.24 mW/cm² for radio frequency:
- 24Mx above the Building Biology guideline of 0.1 μW/m²
- 400Kx above the BioInitiative Report recommendation of 0.0006 μW/cm²
This study used 30 V/m for electric fields:
- 100x above the Building Biology guideline of 0.3 V/m
This study used 0.6 W/kg for SAR (device absorption):
- 1.5x above the Building Biology guideline of 0.4 W/kg
Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.
Where This Falls on the Concern Scale
Study Details
The aim of this study is to investigate the radioprotective effect of bee venom against DNA damage induced by 915-MHz microwave radiation (specific absorption rate of 0.6 W/kg) in Wistar rats.
Whole blood lymphocytes of Wistar rats are treated with 1 μg/mL bee venom 4 hours prior to and immed...
Bee venom shows a decrease in DNA damage compared with irradiated samples. Parameters of Fpg-modifie...
Bee venom is demonstrated to have a radioprotective effect against basal and oxidative DNA damage. Furthermore, bee venom is not genotoxic and does not produce oxidative damage in the low concentrations used in this study.
Show BibTeX
@article{g_2009_radioprotective_effects_of_honeybee_14,
author = {Gajski G and Garaj-Vrhovac V.},
title = {Radioprotective effects of honeybee venom (Apismellifera) against 915-MHz microwave radiation-induced DNA damage in wistar rat lymphocytes: in vitro study.},
year = {2009},
url = {http://ijt.sagepub.com/content/28/2/88.short},
}