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Reproductive Health

The influence of 1800 MHz GSM-like signals on blood chemistry and oxidative stress in non-pregnant and pregnant rabbits.

No Effects Found

Kismali G, Ozgur E, Guler G, Akcay A, Sel T, Seyhan N. · 2012

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Brief daily cell phone radiation exposure caused heart stress markers in pregnant rabbits, suggesting vulnerability during pregnancy.

Plain English Summary

Summary written for general audiences

Researchers exposed pregnant and non-pregnant rabbits to cell phone-like radiation for 15 minutes daily for a week to study potential health effects during pregnancy. While the study found no evidence of oxidative stress (cellular damage from harmful molecules), it did detect changes in blood chemistry markers, particularly enzymes that indicate heart muscle stress. The findings suggest that even brief daily exposure to radiofrequency radiation may affect certain biological processes, especially during pregnancy.

Why This Matters

This study adds important data to our understanding of EMF effects during pregnancy, a particularly vulnerable period. While the researchers found no oxidative stress markers, the changes in creatine kinase enzymes (CK and CK-MB) are noteworthy because these typically indicate heart muscle damage or stress. The reality is that pregnant women today carry phones constantly and live in environments with far more prolonged RF exposure than the 15 minutes daily used in this study. What makes this research valuable is its focus on pregnancy, when developing organisms may be more susceptible to environmental stressors. The science demonstrates that even relatively brief exposures can produce measurable biological changes, reinforcing the need for precautionary approaches during pregnancy.

Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 1.80 GHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 1.80 GHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

Specific exposure levels were not quantified in this study. The study examined exposure from: 1800 MHz Duration: 15 min/day

Study Details

We aimed to investigate the possible effects of radiofrequency radiation (RFR) generated from these devices on oversensitive animals, such as pregnant rabbits.

In the present study, the effects of whole body 1800 MHz Global System for Mobile Communications (GS...

Lipid peroxidation, namely malondialdehyde (MDA) levels, did not change after RFR exposure. However,...

Our investigations have been shown that no indication for oxidative stress was detected in the blood of pregnant rabbits upon RF exposure at specific conditions employed in the present study. Minor changes in some blood chemistry parameters were detected but CK-MB and CK increases were found remarkable. Studies on RFR exposure during pregnancy will help establish international standards for the protection of pregnant women from environmental RFR

Cite This Study
Kismali G, Ozgur E, Guler G, Akcay A, Sel T, Seyhan N. (2012). The influence of 1800 MHz GSM-like signals on blood chemistry and oxidative stress in non-pregnant and pregnant rabbits. Int J Radiat Biol. 88(5):414-419, 2012.
Show BibTeX
@article{g_2012_the_influence_of_1800_2881,
  author = {Kismali G and Ozgur E and Guler G and Akcay A and Sel T and Seyhan N.},
  title = {The influence of 1800 MHz GSM-like signals on blood chemistry and oxidative stress in non-pregnant and pregnant rabbits.},
  year = {2012},
  doi = {10.3109/09553002.2012.661517},
  url = {https://www.tandfonline.com/doi/abs/10.3109/09553002.2012.661517},
}
DOI: 10.3109/09553002.2012.661517

Cited By (35 papers)

Quick Questions About This Study

A 2012 study found that 15-minute daily exposures to 1800 MHz GSM radiation for one week changed several blood chemistry markers in pregnant and non-pregnant rabbits, including cholesterol, protein levels, and heart muscle enzymes like creatine kinase, though no oxidative stress was detected.
Research on rabbits exposed to 1800 MHz radiation for just 15 minutes daily showed notable increases in creatine kinase (CK) and CK-MB enzymes, which typically indicate heart muscle stress, suggesting even short exposures may affect cardiac markers.
A rabbit study using 1800 MHz GSM-like signals found no evidence of oxidative stress in pregnant animals after one week of daily 15-minute exposures, as measured by malondialdehyde levels, though other blood chemistry changes occurred.
Research comparing pregnant and non-pregnant rabbits exposed to 1800 MHz GSM radiation showed that pregnancy itself, combined with radiation exposure, influenced blood chemistry parameters differently than radiation exposure alone, suggesting increased biological sensitivity during pregnancy.
A 2012 study found that 15-minute daily exposures for seven days to 1800 MHz GSM radiation altered cholesterol, total protein, albumin, uric acid, creatinin, and notably increased heart-related enzymes creatine kinase and CK-MB in rabbits.