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Lack of effect of 50-Hz magnetic field exposure on the binding affinity of serotonin for the 5-HT 1B receptor subtype.

No Effects Found

Masuda H, de Gannes FP, Haro E, Billaudel B, Ruffié G, Lagroye I, Veyret B. · 2011

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50-Hz magnetic fields at occupational exposure levels don't affect serotonin receptor binding in brain tissue.

Plain English Summary

Summary written for general audiences

Researchers exposed rat brain tissue and human cells to 50-Hz magnetic fields at 1 milliTesla (similar to levels near power lines) to see if this affected serotonin receptors, which are important for brain function and mood. They found no changes in how serotonin bound to these receptors or in the cellular responses that follow. This suggests that magnetic field exposure at this level doesn't interfere with this particular brain signaling pathway.

Study Details

The aim of this study was to investigate whether the exposure to MF affects binding to the 5-HT1B receptor and a physiological function associated with 5-HT1B receptor activation.

Rat brain crude membrane fractions, including 5-HT1B receptor and C6-glial cells transfected with hu...

In the rat crude membrane, there was no significant difference in the affinity constant of [3H]-5-HT...

This study thus failed to confirm the previous results and findings suggest that exposure to MF below the current occupational limit does not affect the physiological function involved in 5-HT1B receptor subtypes.

Cite This Study
Masuda H, de Gannes FP, Haro E, Billaudel B, Ruffié G, Lagroye I, Veyret B. (2011). Lack of effect of 50-Hz magnetic field exposure on the binding affinity of serotonin for the 5-HT 1B receptor subtype. Brain Res. 1368:44-51, 2011.
Show BibTeX
@article{h_2011_lack_of_effect_of_2830,
  author = {Masuda H and de Gannes FP and Haro E and Billaudel B and Ruffié G and Lagroye I and Veyret B.},
  title = {Lack of effect of 50-Hz magnetic field exposure on the binding affinity of serotonin for the 5-HT 1B receptor subtype.},
  year = {2011},
  
  url = {https://www.sciencedirect.com/science/article/abs/pii/S0006899310024467},
}

Quick Questions About This Study

Researchers exposed rat brain tissue and human cells to 50-Hz magnetic fields at 1 milliTesla (similar to levels near power lines) to see if this affected serotonin receptors, which are important for brain function and mood. They found no changes in how serotonin bound to these receptors or in the cellular responses that follow. This suggests that magnetic field exposure at this level doesn't interfere with this particular brain signaling pathway.