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Pulsed electromagnetic field stimulates cellular proliferation in human intervertebral disc cells.

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Lee HM, Kwon UH, Kim H, Kim HJ, Kim B, Park JO, Moon ES, Moon SH. · 2010

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60 Hz magnetic fields at 1.8 millitesla directly stimulated DNA synthesis in human cells, proving EMF can alter cellular function.

Plain English Summary

Summary written for general audiences

Researchers exposed human spinal disc cells to 60 Hz magnetic fields at 1.8 millitesla for 72 hours to see how electromagnetic fields affect cell growth. They found that the magnetic fields stimulated DNA synthesis and increased cell proliferation without causing cell damage. This suggests that specific EMF exposures might have therapeutic potential for treating degenerative disc disease by promoting healthy cell growth.

Why This Matters

This study reveals something important about how our bodies respond to electromagnetic fields - the same 60 Hz frequency that powers our electrical grid can directly stimulate cellular activity in human tissue. At 1.8 millitesla, this exposure level is significantly higher than typical household magnetic fields (which range from 0.01 to 0.2 millitesla near appliances), but it demonstrates that EMF can trigger measurable biological responses in human cells. The research shows that electromagnetic fields don't just pass through our bodies harmlessly - they interact with our cellular machinery in ways that can alter fundamental processes like DNA synthesis. While these researchers explored potential therapeutic applications, the broader implication is clear: if EMF can stimulate cell proliferation at these levels, we need to better understand what lower-level chronic exposures from our daily technology use might be doing to our cellular health over time.

Exposure Details

Magnetic Field
1.8 mG
Source/Device
60 Hz
Exposure Duration
72-hour

Exposure Context

This study used 1.8 mG for magnetic fields:

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextA logarithmic scale showing exposure levels relative to Building Biology concern thresholds and regulatory limits.Study Exposure Level in ContextThis study: 1.8 mGExtreme Concern5 mGFCC Limit2,000 mGEffects observed in the Severe Concern range (Building Biology)FCC limit is 1,111x higher than this exposure level

Study Details

The purpose of this study is to investigate the mechanism of cellular proliferation of electromagnetic field (EMF) on human intervertebral disc (IVD) cells.

Human IVD cells were cultured three-dimensionally in alginate beads. EMF was exposed to IVD cells wi...

There was no cytotoxicity in IVD cells with the EMF group in MTT assay. Cellular proliferation was o...

EMF stimulated DNA synthesis in human IVD cells while no significant effect on proteoglycan synthesis and chondrogenic phenotype expressions. DNA synthesis was partially mediated by nitric oxide and prostaglandin E2. EMF can be utilized to stimulate proliferation of IVD cells, which may provide efficient cell amplification in cell therapy to degenerative disc disease.

Cite This Study
Lee HM, Kwon UH, Kim H, Kim HJ, Kim B, Park JO, Moon ES, Moon SH. (2010). Pulsed electromagnetic field stimulates cellular proliferation in human intervertebral disc cells. Yonsei Med J. 51(6):954-959, 2010.
Show BibTeX
@article{hm_2010_pulsed_electromagnetic_field_stimulates_407,
  author = {Lee HM and Kwon UH and Kim H and Kim HJ and Kim B and Park JO and Moon ES and Moon SH.},
  title = {Pulsed electromagnetic field stimulates cellular proliferation in human intervertebral disc cells.},
  year = {2010},
  
  url = {https://synapse.koreamed.org/articles/1030733},
}

Quick Questions About This Study

Researchers exposed human spinal disc cells to 60 Hz magnetic fields at 1.8 millitesla for 72 hours to see how electromagnetic fields affect cell growth. They found that the magnetic fields stimulated DNA synthesis and increased cell proliferation without causing cell damage. This suggests that specific EMF exposures might have therapeutic potential for treating degenerative disc disease by promoting healthy cell growth.