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Effects of 900-MHz electromagnetic field emitted from cellular phone on brain oxidative stress and some vitamin levels of guinea pigs.

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Meral I, Mert H, Mert N, Deger Y, Yoruk I, Yetkin A, Keskin S. · 2007

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Researchers concluded that electromagnetic field emitted from a cellular phone might produce oxidative stress in brain tissue of guinea pigs.

Plain English Summary

Summary written for general audiences

In brain tissue, the MDA level increased and GSH level and CAT enzyme activity decreased in EMF-exposed guinea pigs, while vitamins A, E, and D3 levels did not change. In blood, MDA, vitamins A, D3, and E levels, and CAT enzyme activity increased, while GSH level decreased in the EMF-exposed guinea pigs.

Why This Matters

Fourteen male guinea pigs were randomly divided into two groups of seven: a control group and a treatment group exposed to the electromagnetic field. Control guinea pigs were housed in a separate room without exposure to the electromagnetic field. Blood and brain samples were collected after the 30-day experimental period for biochemical analysis. The researchers noted that more studies are needed to demonstrate whether these effects are harmful or affect neural functions.

Exposure Details

SAR
0.95 W/kg
Source/Device
890- to 915-MHz EMF
Exposure Duration
12 h/day (11-h 45-min stand-by and 15-min spiking mode) for 30 days

Exposure Context

This study used 0.95 W/kg for SAR (device absorption):

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextStudy Exposure Level in ContextThis study: 0.95 W/kgExtreme Concern - 0.1 W/kgFCC Limit - 1.6 W/kgEffects observed in the Extreme Concern range (Building Biology)FCC limit is 2 times higher than this level
A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 915 MHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 915 MHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

Study Details

This study was designed to demonstrate the effects of 900-MHz electromagnetic field (EMF) emitted from cellular phone on brain tissue and also blood malondialdehyde (MDA), glutathione (GSH), retinol (vitamin A), vitamin D3 and tocopherol (vitamin E) levels, and catalase (CAT) enzyme activity of guinea pigs.

Fourteen male guinea pigs, weighing 500–800 g were randomly divided into one of two experimental gro...

It was found that the MDA level increased (P < 0.05), GSH level and CAT enzyme activity decreased (P...

It was concluded that electromagnetic field emitted from cellular phone might produce oxidative stress in brain tissue of guinea pigs. However, more studies are needed to demonstrate whether these effects are harmful or/and affect the neural functions.

Cite This Study
Meral I, Mert H, Mert N, Deger Y, Yoruk I, Yetkin A, Keskin S. (2007). Effects of 900-MHz electromagnetic field emitted from cellular phone on brain oxidative stress and some vitamin levels of guinea pigs. Brain Res. 1169:120-124, 2007.
Show BibTeX
@article{i_2007_effects_of_900mhz_electromagnetic_146,
  author = {Meral I and Mert H and Mert N and Deger Y and Yoruk I and Yetkin A and Keskin S.},
  title = {Effects of 900-MHz electromagnetic field emitted from cellular phone on brain oxidative stress and some vitamin levels of guinea pigs.},
  year = {2007},
  
  url = {https://www.sciencedirect.com/science/article/abs/pii/S0006899307015910},
}

Quick Questions About This Study

Fourteen male guinea pigs weighing 500 to 800 g were used, divided into two groups of seven.
Animals were exposed to 890- to 915-MHz electromagnetic field at a SAR of 0.95 W/kg for 12 hours per day for 30 days.
Vitamins A, E, and D3 levels did not change significantly in the brain tissue of EMF-exposed guinea pigs.
The researchers concluded that electromagnetic field emitted from a cellular phone might produce oxidative stress in brain tissue of guinea pigs.
GSH level decreased significantly in the blood of EMF-exposed guinea pigs.