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Biochemical and histopathological effects on the rat testis after exposure to electromagnetic field during fetal period.

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Sehitoglu I, Tumkaya L, Kalkan Y, Bedir R, Cure MC, Zorba OU, Cure E, Yuce S · 2015

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Prenatal exposure to 900 MHz cell-phone radiation lowered serum testosterone, raised caspase-3 activity, and reduced Johnsen scores in male rat offspring at 60 days.

Plain English Summary

Summary written for general audiences

Pregnant rats were exposed to 900 MHz cell-phone radiation 24 hours a day for 20 days throughout pregnancy. Seven male offspring from each group were evaluated at 60 days, with testicular size, weight, histology, and serum testosterone measured. Exposed males had lower serum testosterone (3.51±0.21 ng/ml vs 4.04±0.47 ng/ml, p=0.018), higher caspase-3 activity (2.00±0.88 vs 1.00±0.63, p=0.026), and lower Johnsen scores (8.4±0.5 vs 9.4±0.5, p=0.010) than controls.

Why This Matters

The study included six pregnant rats, with three assigned to the exposure group and three to the control group. The authors concluded that prenatal electromagnetic-field exposure may reduce testicular size, weight, and testosterone while modestly increasing apoptosis.

Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 900 MHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 900 MHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

Specific exposure levels were not quantified in this study. The study examined exposure from: 900 MHz Duration: 24 hours a day for 20 days

Study Details

Electromagnetic radiation (ER) emitted from cell phones may exert a detrimental influence on human health and may affect the man reproductive system. We aimed to study the biological and morphological effects on the testes of 60-day-old male rats after ER exposure (900 MHz), which was applied continuously throughout embryogenesis.

A total of six pregnant Sprague Dawley rats were included in the study. Three pregnant rats (experim...

While serum T level (3.51±0.21 ng/ml) of ER Exposed group was significantly lower than the control g...

Our study demonstrated that ER exposure throughout embryogenesis may cause reductions in serum total T levels and in the size and weight of the testes of male rats, while causing modest increase in apoptosis.

Cite This Study
Sehitoglu I, Tumkaya L, Kalkan Y, Bedir R, Cure MC, Zorba OU, Cure E, Yuce S (2015). Biochemical and histopathological effects on the rat testis after exposure to electromagnetic field during fetal period. Arch Esp Urol. 68(6):562-568, 2015.
Show BibTeX
@article{i_2015_biochemical_and_histopathological_effects_2578,
  author = {Sehitoglu I and Tumkaya L and Kalkan Y and Bedir R and Cure MC and Zorba OU and Cure E and Yuce S},
  title = {Biochemical and histopathological effects on the rat testis after exposure to electromagnetic field during fetal period.},
  year = {2015},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/26179793/},
}

Cited By (16 papers)

Quick Questions About This Study

Pregnant rats were exposed to 900 MHz cell-phone radiation in talking mode continuously for 20 days.
Seven male offspring from the exposed group and seven from the control group were examined.
Exposed males had lower serum testosterone, higher caspase-3 activity, and lower Johnsen scores than controls.
The authors reported that prenatal exposure may cause reductions in the size and weight of the testes.
Serum testosterone was significantly lower in the exposed group (p=0.018).