Radiofrequency radiation (900 MHz)-induced DNA damage and cell cycle arrest in testicular germ cells in swiss albino mice.
Pandey N, Giri S, Das S, Upadhaya P. · 2017
View Original AbstractCell phone-frequency radiation significantly damaged sperm-producing cells and reduced sperm counts in mice through DNA damage and disrupted cell development.
Plain English Summary
Researchers exposed male mice to 900 MHz radiofrequency radiation (similar to cell phone frequencies) for 4-8 hours daily over 35 days and found significant damage to sperm-producing cells in the testes. The radiation disrupted the normal development of sperm cells, caused DNA damage, and reduced sperm counts by interfering with cellular energy production. While the effects were reversible after stopping exposure, the study demonstrates how RF radiation can impair male fertility at the cellular level.
Why This Matters
This research adds important evidence to the growing body of science linking radiofrequency radiation to reproductive health problems in males. The 900 MHz frequency used mirrors cell phone radiation, making these findings directly relevant to everyday exposure scenarios. What's particularly significant is that the researchers documented the precise mechanism of damage - RF radiation disrupted mitochondrial function (the cell's power plants), triggering oxidative stress that damaged DNA and arrested normal sperm development. The fact that effects were partially reversible after exposure stopped offers some hope, but also raises questions about chronic, ongoing exposure from devices we use daily. The science demonstrates that RF radiation can interfere with one of our most fundamental biological processes - reproduction - even when the damage isn't immediately apparent.
Exposure Information
Specific exposure levels were not quantified in this study. The study examined exposure from: 900 MHz Duration: 4 h and 8 h duration per day for 35 days
Study Details
This study evaluates alterations in male germ cell transformation kinetics following RFR exposure and after recovery.
Swiss albino mice were exposed to RFR (900 MHz) for 4 h and 8 h duration per day for 35 days. One gr...
RFR exposure caused depolarization of mitochondrial membranes resulting in destabilized cellular red...
To conclude, RFR exposure-induced oxidative stress causes DNA damage in germ cells, which alters cell cycle progression leading to low sperm count in mice.
Show BibTeX
@article{n_2017_radiofrequency_radiation_900_mhzinduced_1695,
author = {Pandey N and Giri S and Das S and Upadhaya P.},
title = {Radiofrequency radiation (900 MHz)-induced DNA damage and cell cycle arrest in testicular germ cells in swiss albino mice.},
year = {2017},
doi = {10.1177/0748233716671206},
url = {https://journals.sagepub.com/doi/abs/10.1177/0748233716671206},
}