Effect of electromagnetic radiation on discharge activity of neurons in the hippocampus CA1 in rats
Tong J, Chen S, Liu XM, Hao DM · 2013
View Original AbstractElectromagnetic radiation at 900 MHz appeared to reduce discharge frequency and alter firing patterns in rat hippocampal CA1 neurons.
Plain English Summary
Researchers recorded hippocampal CA1 neuron activity in rats exposed to 900 MHz electromagnetic radiation at 10 W/m2 using glass electrode extracellular recording and a polygraph. Discharge frequency of hippocampal CA1 neurons was reduced after exposure, though the change in scale was not obvious. Electromagnetic radiation might change the spontaneous discharge patterns of hippocampus CA1 region neurons, making the explosive discharge pattern increase obviously. The researchers suggested that these changes may lead to a decrease in the ability of learning and memory.
Why This Matters
In the glass electrode recording experiments, rats were separately irradiated for 10, 20, 30, 40, 50, and 60 minutes, with each time point repeated 10 times and an update interval of 1 hour. In the polygraph recording experiments, the irradiation group was exposed for 5 days a week, 6 hours per day, for 10 weeks, with implanted electrodes monitoring electrical changes. Peak potential total number within 5 minutes in the irradiation group was significantly reduced, and the largest amplitude was less than that of the control group. A correlation analysis found that the irradiation group result was less than that of the control group, indicating a tendency toward inhibitory connections between neurons after electromagnetic radiation.
Exposure Details
- Power Density
- 1 mW/cm²
- Source/Device
- 900 MHZ
- Exposure Duration
- 10, 20, 30, 40, 50 and 60 min
Exposure Context
This study used 1 mW/cm² for radio frequency:
- 100Mx above the Building Biology guideline of 0.1 μW/m²
- 1.7Mx above the BioInitiative Report recommendation of 0.0006 μW/cm²
Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.
Where This Falls on the Concern Scale
Study Details
In order to explore effect of electromagnetic radiation on learning and memory ability of hippocampus neuron in rats, the changes in discharge patterns and overall electrical activity of hippocampus neuron after electromagnetic radiation were observed
Rat neurons discharge was recorded with glass electrode extracellular recording technology and a pol...
Electromagnetic radiation had an inhibitory role on discharge frequency of the hippocampus CA1 regio...
Electromagnetic radiation may cause structure and function changes of transfer synaptic in global, make hippocampal CA1 area neurons change in the overall discharge characteristic and discharge patterns, thus lead to decrease in the ability of learning and memory.
Show BibTeX
@article{j_2013_effect_of_electromagnetic_radiation_193,
author = {Tong J and Chen S and Liu XM and Hao DM},
title = {Effect of electromagnetic radiation on discharge activity of neurons in the hippocampus CA1 in rats},
year = {2013},
url = {https://europepmc.org/article/med/24386818},
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