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Note: This study found no significant biological effects under its experimental conditions. We include all studies for scientific completeness.

DNA & Genetic Damage

Effect of radiofrequency radiation on mRNA expression in cultured rodent cells.

No Effects Found

Parker JE, Kiel JL, Winters WD · 1988

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High-power microwave radiation showed no immediate gene expression changes in lab cells, but this doesn't address long-term effects from typical device exposure.

Plain English Summary

Summary written for general audiences

Researchers exposed four types of rodent cells to 2450 MHz microwave radiation (the same frequency as microwave ovens) at very high power levels to see if it would change how genes are expressed. They found no significant differences in gene activity between exposed and unexposed cells, even when testing genes related to cancer development and cellular stress responses.

Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 2.45 GHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 2.45 GHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

The study examined exposure from: 2450 MHz

Study Details

To study the effect of radiofrequency radiation on mRNA expression in cultured rodent cells

Four rodent cell lines were exposed to 2450 MHz microwave radiation at a Specific Absorption Rate (S...

With the cell lines and probes used in this study no significant differences in mRNA expression were...

Cite This Study
Parker JE, Kiel JL, Winters WD (1988). Effect of radiofrequency radiation on mRNA expression in cultured rodent cells. Physiol Chem Phys Med NMR 20(2):129-134, 1988. .
Show BibTeX
@article{je_1988_effect_of_radiofrequency_radiation_3298,
  author = {Parker JE and Kiel JL and Winters WD},
  title = {Effect of radiofrequency radiation on mRNA expression in cultured rodent cells.},
  year = {1988},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/3222348/},
}
PubMed: 3222348

Cited By (10 papers)

Quick Questions About This Study

A 1988 study found no DNA damage from 2450 MHz microwave radiation in rodent cells, even at very high power levels. However, this represents just one study using specific cell types and exposure conditions, so more research is needed for definitive conclusions.
Research by Parker and colleagues found no significant changes in gene expression when rodent cells were exposed to 2450 MHz radiation. The study tested multiple cell types and examined genes related to cancer and stress responses with no observable effects.
One laboratory study using the same 2450 MHz frequency as microwave ovens found no harmful effects on cultured rodent cells. The researchers exposed cells to very high power levels but observed no changes in genetic activity or cellular responses.
This 1988 study found no genetic risks from radiofrequency radiation at 2450 MHz in laboratory cell cultures. However, this single study cannot definitively rule out all genetic effects, as research continues to examine various RF frequencies and exposure scenarios.
Laboratory research showed no impact on cellular stress responses from 2450 MHz microwave radiation. Scientists specifically examined genes that activate during cellular stress and found no significant differences between exposed and unexposed rodent cells, even at high power levels.