Note: This study found no significant biological effects under its experimental conditions. We include all studies for scientific completeness.
DNA damage and micronucleus induction in human leukocytes after acute in vitro exposure to a 1.9 GHz continuous-wave radiofrequency field.
McNamee JP, Bellier PV, Gajda GB, Miller SM, Lemay EP, Lavallee BF, Marro L, Thansandote A. · 2002
View Original AbstractThe study found no evidence of increased DNA damage or micronucleus formation in human leukocytes after acute exposure to a 1.9 GHz continuous-wave radiofrequency field at any SAR tested.
Plain English Summary
Human blood cultures were exposed to a 1.9 GHz continuous-wave radiofrequency field for 2 hours at SARs of 0.0, 0.1, 0.26, 0.92, 2.4, and 10 W/kg while temperature was maintained at 37.0 ± 0.5°C. DNA damage was measured immediately after exposure using the alkaline comet assay with four parameters, and micronucleus formation was assessed using the cytokinesis-block micronucleus assay. No evidence of increased primary DNA damage was detected at any SAR tested. There was no significant difference in micronucleus incidence between exposed cultures and sham controls at any SAR.
Why This Matters
The aim of the study was to observe DNA damage and micronucleus induction in human leukocytes after acute in vitro exposure to a 1.9 GHz continuous-wave radiofrequency field. The authors concluded that the results do not support the hypothesis that acute, nonthermalizing 1.9 GHz CW RF-field exposure causes DNA damage in cultured human leukocytes.
Exposure Details
- SAR
- 0.0, 0.1, 0.26, 0.92, 2.4 and 10 W/kg
- Source/Device
- 1.9 GHz
- Exposure Duration
- 2 h
Where This Falls on the Concern Scale
Study Details
The aim of the study is to observe DNA damage and micronucleus induction in human leukocytes after acute in vitro exposure to a 1.9 GHz continuous-wave radiofrequency field.
Human blood cultures were exposed to a 1.9 GHz continuous-wave (CW) radiofrequency (RF) field for 2 ...
No evidence of increased primary DNA damage was detected by any parameter for RF-field-exposed cultu...
These results do not support the hypothesis that acute, nonthermalizing 1.9 GHz CW RF-field exposure causes DNA damage in cultured human leukocytes.
Show BibTeX
@article{jp_2002_dna_damage_and_micronucleus_2922,
author = {McNamee JP and Bellier PV and Gajda GB and Miller SM and Lemay EP and Lavallee BF and Marro L and Thansandote A.},
title = {DNA damage and micronucleus induction in human leukocytes after acute in vitro exposure to a 1.9 GHz continuous-wave radiofrequency field.},
year = {2002},
url = {https://meridian.allenpress.com/radiation-research/article-abstract/158/4/523/331871/DNA-Damage-and-Micronucleus-Induction-in-Human},
}