3,138 Studies Reviewed. 77.4% Found Biological Effects. The Evidence is Clear.

Note: This study found no significant biological effects under its experimental conditions. We include all studies for scientific completeness.

Microarray gene expression profiling of a human glioblastoma cell line exposed in vitro to a 1.9 GHz pulse-modulated radiofrequency field.

No Effects Found

Qutob SS, Chauhan V, Bellier PV, Yauk CL, Douglas GR, Berndt L, Williams A, Gajda GB, Lemay E, Thansandote A, McNamee JP. · 2006

View Original Abstract
Share:

Brain cancer cells showed no gene expression changes after 4-hour RF exposure up to 10 W/kg, though longer-term effects remain unstudied.

Plain English Summary

Summary written for general audiences

Researchers exposed human brain cancer cells (glioblastoma) to 1.9 GHz radiofrequency radiation for 4 hours at power levels ranging from very low to quite high (0.1 to 10 W/kg SAR). They found no changes in gene expression at any exposure level, while heat treatment successfully triggered expected cellular stress responses. This suggests that RF fields at these levels don't alter how genes function in these particular brain cells.

Study Details

The purpose of this study was to assess the ability of exposure to a 1.9 GHz pulse-modulated RF field for 4 h at specific absorption rates (SARs) of 0.1, 1.0 and 10.0 W/kg to affect global gene expression in U87MG glioblastoma cells.

We found no evidence that non-thermal RF fields can affect gene expression in cultured U87MG cells r...

Future studies will assess the effect of RF fields on other cell lines and on gene expression in the mouse brain after in vivo exposure.

Cite This Study
Qutob SS, Chauhan V, Bellier PV, Yauk CL, Douglas GR, Berndt L, Williams A, Gajda GB, Lemay E, Thansandote A, McNamee JP. (2006). Microarray gene expression profiling of a human glioblastoma cell line exposed in vitro to a 1.9 GHz pulse-modulated radiofrequency field. Radiat Res. 165(6):636-644, 2006.
Show BibTeX
@article{ss_2006_microarray_gene_expression_profiling_3316,
  author = {Qutob SS and Chauhan V and Bellier PV and Yauk CL and Douglas GR and Berndt L and Williams A and Gajda GB and Lemay E and Thansandote A and McNamee JP.},
  title = {Microarray gene expression profiling of a human glioblastoma cell line exposed in vitro to a 1.9 GHz pulse-modulated radiofrequency field.},
  year = {2006},
  
  url = {https://bioone.org/journals/radiation-research/volume-165/issue-6/RR3561.1/Microarray-Gene-Expression-Profiling-of-a-Human-Glioblastoma-Cell-Line/10.1667/RR3561.1.short},
}

Quick Questions About This Study

Researchers exposed human brain cancer cells (glioblastoma) to 1.9 GHz radiofrequency radiation for 4 hours at power levels ranging from very low to quite high (0.1 to 10 W/kg SAR). They found no changes in gene expression at any exposure level, while heat treatment successfully triggered expected cellular stress responses. This suggests that RF fields at these levels don't alter how genes function in these particular brain cells.