Note: This study found no significant biological effects under its experimental conditions. We include all studies for scientific completeness.
Effects of 1.8 GHz Radiofrequency Fields on the Emotional Behavior and Spatial Memory of Adolescent Mice.
Zhang JP, Zhang KY, Guo L, Chen QL, Gao P, Wang T, Li J, Guo GZ, Ding GR. · 2017
View Original AbstractAdolescent male mice exposed to 1.8 GHz RF for 4 weeks showed increased anxiety-like behavior and reduced cortical and hippocampal GABA and aspartic acid, while depression-like behavior, spatial memory, and brain histology were unchanged.
Plain English Summary
Researchers exposed adolescent male mice to a 1.8 GHz radiofrequency field for 4 weeks. Depression-like behavior, spatial memory ability, and brain histology did not change obviously after exposure. Anxiety-like behavior increased, and levels of GABA and aspartic acid in the cortex and hippocampus significantly decreased.
Why This Matters
The authors interpreted the findings as suggesting that RF exposure may increase anxiety with GABA and aspartic acid likely involved. Anxiety-like behavior was assessed using open field and elevated plus maze tests. Depression-like behavior was measured with sucrose preference, tail suspension, and forced swim tests, while spatial memory was tested in the Morris water maze. Brain neurotransmitter levels were determined by liquid chromatography-mass spectrometry and histology by hematoxylin-eosin staining.
Exposure Information
Specific exposure levels were not quantified in this study. The study examined exposure from: 1.8 GHz
Study Details
In this study, we investigated the effects of 4-week exposure to a 1.8 GHz RF field on the emotional behavior and spatial memory of adolescent male mice.
Anxiety-like behavior was evaluated by open field test (OFT) and elevated plus maze (EPM) test, whil...
It was found that the depression-like behavior, spatial memory ability and histology of the brain di...
These data suggested that RF exposure under these conditions do not affect the depression-like behavior, spatial memory and brain histology in adolescent male mice, but it may however increase the level of anxiety, and GABA and Asp were probably involved in this effect.
Show BibTeX
@article{jp_2017_effects_of_18_ghz_3504,
author = {Zhang JP and Zhang KY and Guo L and Chen QL and Gao P and Wang T and Li J and Guo GZ and Ding GR.},
title = {Effects of 1.8 GHz Radiofrequency Fields on the Emotional Behavior and Spatial Memory of Adolescent Mice.},
year = {2017},
url = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707983/},
}