8,700 Studies Reviewed. 87.0% Found Biological Effects. The Evidence is Clear.
Shield Your Body

Note: This study found no significant biological effects under its experimental conditions. We include all studies for scientific completeness.

Brain & Nervous System

Heat shock protein induction in fetal mouse brain as a measure of stress after whole of gestation exposure to mobile telephony radiofrequency fields

No Effects Found

Finnie JW, Chidlow G, Blumbergs PC, Manavis J, Cai Z · 2009

View Original Abstract
Share:

Fetal mouse brains showed no stress response to 4 W/kg cell phone radiation throughout pregnancy, suggesting resilience to high-level RF exposure.

Plain English Summary

Summary written for general audiences

Researchers exposed pregnant mice to 900 MHz cell phone radiation (at 4 W/kg) for one hour daily throughout pregnancy to see if it caused stress in developing fetal brains. They found no evidence of cellular stress responses when they examined the brain tissue using specialized markers called heat shock proteins. This suggests that this level of radiofrequency exposure during pregnancy may not trigger detectable stress responses in developing brain tissue.

Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 900 MHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 900 MHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

The study examined exposure from: 900 MHz Duration: 60 min/day from day 1 to day 19 of gestation

Study Details

To determine whether whole of gestation exposure of fetal mouse brain to mobile telephone radiofrequency fields produces a stress response detectable by induction of heat shock proteins (HSPs).

Using a purpose-designed exposure system at 900 MHz, pregnant mice were given a single, far-field, w...

There was no induction of HSP32 or 70 in any brains, while HSP25 expression was limited to two brain...

Whole of gestation exposure of fetal mouse brains to mobile phone radiofrequency fields did not produce any stress response using HSPs as an immunohistochemical marker.

Cite This Study
Finnie JW, Chidlow G, Blumbergs PC, Manavis J, Cai Z (2009). Heat shock protein induction in fetal mouse brain as a measure of stress after whole of gestation exposure to mobile telephony radiofrequency fields Pathology. 41(3):276-279, 2009b.
Show BibTeX
@article{jw_2009_heat_shock_protein_induction_2753,
  author = {Finnie JW and Chidlow G and Blumbergs PC and Manavis J and Cai Z},
  title = {Heat shock protein induction in fetal mouse brain as a measure of stress after whole of gestation exposure to mobile telephony radiofrequency fields},
  year = {2009},
  
  url = {https://www.sciencedirect.com/science/article/abs/pii/S0031302516320244},
}

Quick Questions About This Study

No, a 2009 study found that daily exposure to 900 MHz cell phone radiation at 4 W/kg throughout pregnancy did not cause detectable stress responses in fetal mouse brains. Heat shock proteins, which indicate cellular stress, showed no abnormal activation in exposed brain tissue.
Heat shock proteins serve as sensitive markers of cellular stress and damage. This 2009 mouse study used HSP25, HSP32, and HSP70 to detect potential brain stress from 900 MHz radiation exposure but found no evidence of stress responses in fetal brain tissue.
A 2009 study exposing pregnant mice to 900 MHz radiation for one hour daily throughout gestation found no detectable stress responses in fetal brains. However, this represents just one study using specific exposure conditions and stress markers in mice.
Research found that HSP25 expression occurred in two brainstem nuclei in both radiation-exposed and non-exposed fetal mouse brains. This normal pattern suggests the 900 MHz exposure at 4 W/kg did not alter typical brainstem protein expression during development.
A 2009 study using 4 W/kg SAR exposure from 900 MHz mobile phone radiation throughout mouse pregnancy found no harmful stress responses in developing brains. Heat shock protein analysis showed no abnormal cellular stress reactions in fetal brain tissue.