Note: This study found no significant biological effects under its experimental conditions. We include all studies for scientific completeness.
Heat shock protein induction in fetal mouse brain as a measure of stress after whole of gestation exposure to mobile telephony radiofrequency fields
Finnie JW, Chidlow G, Blumbergs PC, Manavis J, Cai Z · 2009
View Original AbstractWhole-gestation exposure to mobile phone radiofrequency fields did not induce heat shock proteins in fetal mouse brains.
Plain English Summary
Researchers exposed pregnant mice to 900 MHz radiofrequency fields at 4 W/kg for 60 minutes daily throughout gestation. Fetal brains were examined for heat shock proteins HSP25, HSP32, and HSP70. No induction of HSP32 or HSP70 was found in any brains, and HSP25 expression was similar in exposed and control groups. The study concluded that whole-gestation exposure did not produce a stress response detectable by HSPs.
Why This Matters
The study aimed to test if prenatal radiofrequency exposure triggers a stress response measurable by heat shock protein induction. Controls included sham-exposed mice and freely moving mice to account for restraint stress.
Exposure Details
- SAR
- 4 W/kg
- Source/Device
- 900 MHz
- Exposure Duration
- 60 min/day from day 1 to day 19 of gestation
Exposure Context
This study used 4 W/kg for SAR (device absorption):
- 10x above the Building Biology guideline of 0.4 W/kg
Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.
Where This Falls on the Concern Scale
Study Details
To determine whether whole of gestation exposure of fetal mouse brain to mobile telephone radiofrequency fields produces a stress response detectable by induction of heat shock proteins (HSPs).
Using a purpose-designed exposure system at 900 MHz, pregnant mice were given a single, far-field, w...
There was no induction of HSP32 or 70 in any brains, while HSP25 expression was limited to two brain...
Whole of gestation exposure of fetal mouse brains to mobile phone radiofrequency fields did not produce any stress response using HSPs as an immunohistochemical marker.
Show BibTeX
@article{jw_2009_heat_shock_protein_induction_2753,
author = {Finnie JW and Chidlow G and Blumbergs PC and Manavis J and Cai Z},
title = {Heat shock protein induction in fetal mouse brain as a measure of stress after whole of gestation exposure to mobile telephony radiofrequency fields},
year = {2009},
url = {https://www.sciencedirect.com/science/article/abs/pii/S0031302516320244},
}