3,138 Studies Reviewed. 77.4% Found Biological Effects. The Evidence is Clear.

Chronic exposure to an extremely low‐frequency magnetic field induces depression‐like behavior and corticosterone secretion without enhancement of the hypothalamic–pituitary–adrenal axis in mice†

Bioeffects Seen

Kitaoka K, Kitamura M, Aoi S, Shimizu N, Yoshizaki K. · 2013

View Original Abstract
Share:

Chronic magnetic field exposure at 3 milliTesla triggered depression-like behavior and elevated stress hormones in mice.

Plain English Summary

Summary written for general audiences

Researchers exposed mice to extremely low frequency magnetic fields (ELF-MF) at 3 milliTesla for 200 hours and measured their behavior and stress hormone levels. The exposed mice showed significantly more depression and anxiety-like behaviors, along with elevated levels of the stress hormone corticosterone. This suggests that chronic exposure to strong magnetic fields may affect mental health and stress response systems.

Why This Matters

This study adds important evidence to our understanding of how magnetic field exposure affects brain function and mental health. The 3 milliTesla exposure level used here is extremely high compared to typical household sources (which produce fields measured in microTesla), but it's within the range of occupational exposures for workers near industrial equipment or MRI machines. What makes this research particularly significant is that it demonstrates measurable behavioral changes alongside biochemical markers of stress, providing a more complete picture of how EMF exposure might impact wellbeing. The science demonstrates that even without activating the body's primary stress response pathway, magnetic fields can still trigger depression-like symptoms and elevate stress hormones. This challenges the assumption that EMF effects must follow traditional biological pathways to be real.

Exposure Details

Magnetic Field
3 mG
Exposure Duration
200 h

Exposure Context

This study used 3 mG for magnetic fields:

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextA logarithmic scale showing exposure levels relative to Building Biology concern thresholds and regulatory limits.Study Exposure Level in ContextThis study: 3 mGExtreme Concern5 mGFCC Limit2,000 mGEffects observed in the Severe Concern range (Building Biology)FCC limit is 667x higher than this exposure level

Study Details

In the present study, we investigated whether chronic ELF‐MF exposure (intensity, 3 mT; total exposure, 200 h) affected emotional behavior and corticosterone synthesis in mice.

ELF‐MF‐treated mice showed a significant increase in total immobility time in a forced swim test and...

Our findings suggest the possibility that high intensity and chronic exposure to ELF‐MF induces an increase in corticosterone secretion, along with depression‐ and/or anxiety‐like behavior, without enhancement of the hypothalamic–pituitary–adrenal axis.

Cite This Study
Kitaoka K, Kitamura M, Aoi S, Shimizu N, Yoshizaki K. (2013). Chronic exposure to an extremely low‐frequency magnetic field induces depression‐like behavior and corticosterone secretion without enhancement of the hypothalamic–pituitary–adrenal axis in mice† Bioelectromagnetics. 34(1):43-51, 2013.
Show BibTeX
@article{k_2013_chronic_exposure_to_an_266,
  author = {Kitaoka K and Kitamura M and Aoi S and Shimizu N and Yoshizaki K.},
  title = {Chronic exposure to an extremely low‐frequency magnetic field induces depression‐like behavior and corticosterone secretion without enhancement of the hypothalamic–pituitary–adrenal axis in mice†},
  year = {2013},
  doi = {10.1002/bem.21743},
  url = {https://onlinelibrary.wiley.com/doi/abs/10.1002/bem.21743},
}

Quick Questions About This Study

Researchers exposed mice to extremely low frequency magnetic fields (ELF-MF) at 3 milliTesla for 200 hours and measured their behavior and stress hormone levels. The exposed mice showed significantly more depression and anxiety-like behaviors, along with elevated levels of the stress hormone corticosterone. This suggests that chronic exposure to strong magnetic fields may affect mental health and stress response systems.