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The Intracranial Distribution of Gliomas in Relation to Exposure From Mobile Phones: Analyses From the INTERPHONE Study.

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Grell K, Frederiksen K, Schüz J, Cardis E, Armstrong B, Siemiatycki J, Krewski DR, McBride ML, Johansen C, Auvinen A, Hours M, Blettner M, Sadetzki S, Lagorio S, Yamaguchi N, Woodward A, Tynes T, Feychting M, Fleming SJ, Swerdlow AJ, Andersen PK. · 2016

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Brain tumors cluster on the side of the head where people hold their phones, regardless of call duration.

Plain English Summary

Summary written for general audiences

Researchers analyzed 792 brain tumor patients from 13 countries to see if gliomas (a type of brain cancer) occurred more often on the side of the head where people held their cell phones. They found a statistically significant pattern: brain tumors were more likely to develop on the same side of the head where patients reported using their phones most frequently. This spatial relationship held true regardless of how much time people spent on calls, suggesting that location of exposure may be more important than duration.

Why This Matters

This analysis from the massive INTERPHONE study provides compelling evidence for a spatial relationship between cell phone use and brain tumor location. What makes this finding particularly significant is that it's independent of call duration - meaning it's not just about how long you talk, but where you hold the device. The science demonstrates that radiofrequency energy from phones is absorbed in highly localized patterns in brain tissue, and this study shows tumors clustering in those same areas. While the researchers acknowledge potential recall bias, the consistency of this spatial pattern across nearly 800 cases from 13 countries strengthens the biological plausibility of a causal relationship. The reality is that your brain tissue closest to your phone receives the highest radiation dose, and this study suggests that matters more than previously understood.

Exposure Information

Specific exposure levels were not quantified in this study.

Study Details

We used a point process model to investigate this association using information that included tumor localization data from the INTERPHONE Study (Australia, Canada, Denmark, Finland, France, Germany, Israel, Italy, Japan, New Zealand, Norway, Sweden, and the United Kingdom).

Our main analysis included 792 regular mobile phone users diagnosed with a glioma between 2000 and 2...

Similar to earlier results, we found a statistically significant association between the intracrania...

Cite This Study
Grell K, Frederiksen K, Schüz J, Cardis E, Armstrong B, Siemiatycki J, Krewski DR, McBride ML, Johansen C, Auvinen A, Hours M, Blettner M, Sadetzki S, Lagorio S, Yamaguchi N, Woodward A, Tynes T, Feychting M, Fleming SJ, Swerdlow AJ, Andersen PK. (2016). The Intracranial Distribution of Gliomas in Relation to Exposure From Mobile Phones: Analyses From the INTERPHONE Study. Am J Epidemiol. 184(11):818-828, 2016.
Show BibTeX
@article{k_2016_the_intracranial_distribution_of_2124,
  author = {Grell K and Frederiksen K and Schüz J and Cardis E and Armstrong B and Siemiatycki J and Krewski DR and McBride ML and Johansen C and Auvinen A and Hours M and Blettner M and Sadetzki S and Lagorio S and Yamaguchi N and Woodward A and Tynes T and Feychting M and Fleming SJ and Swerdlow AJ and Andersen PK.},
  title = {The Intracranial Distribution of Gliomas in Relation to Exposure From Mobile Phones: Analyses From the INTERPHONE Study.},
  year = {2016},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/27810856/},
}

Quick Questions About This Study

Researchers analyzed 792 brain tumor patients from 13 countries to see if gliomas (a type of brain cancer) occurred more often on the side of the head where people held their cell phones. They found a statistically significant pattern: brain tumors were more likely to develop on the same side of the head where patients reported using their phones most frequently. This spatial relationship held true regardless of how much time people spent on calls, suggesting that location of exposure may be more important than duration.