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Chronic exposure to an extremely low-frequency magnetic field induces depression-like behavior and corticosterone secretion without enhancement of the hypothalamic-pituitary-adrenal axis in mice

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Kazuyoshi Kitaoka K, M Kitamura, S Aoi, N Shimizu, K Yoshizaki · 2013

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Chronic ELF magnetic field exposure produced depression-like behavioral changes and stress hormone elevation in mice through a mechanism that may bypass typical HPA axis enhancement.

Plain English Summary

Summary written for general audiences

This 2013 study in mice examined the effects of chronic exposure to extremely low-frequency (ELF) magnetic fields on behavioral and endocrine outcomes. The researchers found that ELF magnetic field exposure induced depression-like behavior and elevated corticosterone secretion, but did not enhance hypothalamic-pituitary-adrenal (HPA) axis activation.

Why This Matters

This study contributes to the literature on non-thermal biological effects of ELF magnetic fields in animal models. The dissociation between corticosterone elevation and HPA axis activation suggests a potential alternative pathway for stress-related effects from magnetic field exposure.

Exposure Information

Specific exposure levels were not quantified in this study.

Cite This Study
Kazuyoshi Kitaoka K, M Kitamura, S Aoi, N Shimizu, K Yoshizaki (2013). Chronic exposure to an extremely low-frequency magnetic field induces depression-like behavior and corticosterone secretion without enhancement of the hypothalamic-pituitary-adrenal axis in mice.
Show BibTeX
@article{kazuyoshi_kitaoka_k_m_kitamura_s_aoi_n_shimizu_k_yoshizaki_ce4436,
  author = {Kazuyoshi Kitaoka K and M Kitamura and S Aoi and N Shimizu and K Yoshizaki},
  title = {Chronic exposure to an extremely low-frequency magnetic field induces depression-like behavior and corticosterone secretion without enhancement of the hypothalamic-pituitary-adrenal axis in mice},
  year = {2013},
  doi = {10.1016/j.neuropharm.2013.04.009},
  
}
DOI: 10.1016/j.neuropharm.2013.04.009

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