Enhancement of X-ray Induced Apoptosis by Mobile Phone-Like Radio-Frequency Electromagnetic Fields in Mouse Spermatocyte-Derived Cells.
Zhang KY, Xu H, Du L, Xing JL, Zhang B, Bai QS, Xu YQ, Zhou YC, Zhang JP, Zhou Y, Ding GR. · 2017
View Original AbstractRF exposure alone did not affect proliferation or apoptosis in mouse spermatocyte-derived cells, but combined with X-ray it significantly decreased proliferation and increased apoptosis.
Plain English Summary
Researchers exposed mouse spermatocyte-derived GC-1 cells to a 1950 MHz RF field at 3 W/kg SAR for 24 hours with or without 6 Gy X-ray irradiation. RF exposure alone did not change cell proliferation or apoptosis levels. When combined with X-ray, RF exposure significantly decreased proliferation and increased apoptotic rate compared to X-ray alone. The combined exposure also significantly decreased Bcl-2 protein expression and increased Bax protein expression.
Why This Matters
The study aimed to investigate enhancement of X-ray induced apoptosis by mobile phone-like radio-frequency electromagnetic fields in mouse spermatocyte-derived cells. Cell proliferation was measured using MTT and BrdU ELISA assays. Apoptosis was assessed by annexin V flow cytometry, TUNEL assay, and caspase-3 activity assay.
Exposure Details
- SAR
- 3 W/kg
- Source/Device
- 1950 MHz
- Exposure Duration
- 24 hours
Exposure Context
This study used 3 W/kg for SAR (device absorption):
- 7.5x above the Building Biology guideline of 0.4 W/kg
Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.
Where This Falls on the Concern Scale
Study Details
The Aim of this study is to investigate Enhancement of X-ray Induced Apoptosis by Mobile Phone-Like Radio-Frequency Electromagnetic Fields in Mouse Spermatocyte-Derived Cells.
To explore the combined effects of environmental radio-frequency (RF) field and X-ray, mouse spermat...
It was found that the proliferation and apoptosis level did not change in GC-1 cells after RF exposu...
Show BibTeX
@article{ky_2017_enhancement_of_xray_induced_1462,
author = {Zhang KY and Xu H and Du L and Xing JL and Zhang B and Bai QS and Xu YQ and Zhou YC and Zhang JP and Zhou Y and Ding GR.},
title = {Enhancement of X-ray Induced Apoptosis by Mobile Phone-Like Radio-Frequency Electromagnetic Fields in Mouse Spermatocyte-Derived Cells.},
year = {2017},
url = {https://pubmed.ncbi.nlm.nih.gov/28590418/},
}Cited By (6 papers)
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