Effects of modulated microwave radiation at cellular telephone frequency (1.95 GHz) on X-ray-induced chromosome aberrations in human lymphocytes in vitro.
Manti L, Braselmann H, Calabrese ML, Massa R, Pugliese M, Scampoli P, Sicignano G, Grossi G. · 2008
View Original AbstractA 1.95 GHz UMTS signal did not increase the fraction of aberrant cells, but exchanges per cell showed a small, statistically significant increase of 0.11 compared to 0 W/kg SAR.
Plain English Summary
Researchers exposed human peripheral blood lymphocytes in vitro to a UMTS signal at a frequency carrier of 1.95 GHz for 24 hours at 0.5 and 2.0 W/kg SAR. Cells were also given 4 Gy of X rays immediately before RF radiation or sham exposures, and chromosome aberrations were measured by fluorescence in situ hybridization. No significant variations due to the UMTS exposure were found in the fraction of aberrant cells, but the frequency of exchanges per cell showed a small but statistically significant increase of 0.11 exchange per cell compared to 0 W/kg SAR.
Why This Matters
The study tested whether a 1.95 GHz UMTS-modulated signal could worsen chromosome damage already caused by X-rays in human lymphocytes. The researchers found that the 1.95 GHz signal does not exacerbate the yield of aberrant cells caused by ionizing radiation. However, the researchers suggested that the overall burden of X-ray-induced chromosomal damage per cell in first-mitosis lymphocytes may be enhanced at 2.0 W/kg SAR. The researchers concluded that the SAR may either influence the repair of X-ray-induced DNA breaks or alter the cell death pathways of the damage response.
Exposure Details
- SAR
- 0.5 and 2.0 W/kg
- Source/Device
- 1.95 GHz UMTS Cellular Telephone
- Exposure Duration
- 24h
Exposure Context
This study used 0.5 and 2.0 W/kg for SAR (device absorption):
- 1.3x above the Building Biology guideline of 0.4 W/kg
Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.
Where This Falls on the Concern Scale
Study Details
To study the effects of Modulated Microwave Radiation at Cellular Telephone Frequency (1.95 GHz) on X-Ray-Induced Chromosome Aberrations in Human Lymphocytes In Vitro.
Human peripheral blood lymphocytes were exposed in vitro to a UMTS signal (frequency carrier of 1.95...
No significant variations due to the UMTS exposure were found in the fraction of aberrant cells. How...
We conclude that, although the 1.95 GHz signal (UMTS modulated) does not exacerbate the yield of aberrant cells caused by ionizing radiation, the overall burden of X-ray-induced chromosomal damage per cell in first-mitosis lymphocytes may be enhanced at 2.0 W/kg SAR. Hence the SAR may either influence the repair of X-ray-induced DNA breaks or alter the cell death pathways of the damage response.
Show BibTeX
@article{l_2008_effects_of_modulated_microwave_17,
author = {Manti L and Braselmann H and Calabrese ML and Massa R and Pugliese M and Scampoli P and Sicignano G and Grossi G.},
title = {Effects of modulated microwave radiation at cellular telephone frequency (1.95 GHz) on X-ray-induced chromosome aberrations in human lymphocytes in vitro.},
year = {2008},
url = {https://meridian.allenpress.com/radiation-research/article-abstract/169/5/575/42723/Effects-of-Modulated-Microwave-Radiation-at},
}