6,486 Studies Reviewed. 85.2% of Original Studies Found Biological Effects. The Evidence is Clear.
Shield Your Body
Oxidative Stress102 citations

900 MHz pulse-modulated radiofrequency radiation induces oxidative stress on heart, lung, testis and liver tissues

Bioeffects Seen

Esmekaya MA, Ozer C, Seyhan N · 2011

View Original Abstract
Share:

Rats exposed to 900 MHz pulse-modulated RF radiation showed significantly increased oxidative stress markers and lower antioxidant levels in heart, lung, liver, and testis tissues.

Plain English Summary

Summary written for general audiences

Researchers exposed male Wistar albino rats to 900 MHz pulse-modulated RF radiation at a SAR of 1.20 W/kg for 20 minutes per day over three weeks to investigate oxidative damage in multiple tissues. MDA and NOx levels were significantly increased in liver, lung, testis, and heart tissues of the exposed group compared to sham and control groups, while GSH levels were significantly lower in exposed rat tissues. No significant difference was observed between the sham and control groups.

Why This Matters

The study used three groups of ten rats each: an unexposed control group, a sham group with the device off, and an RF-exposed group. Oxidative damage was assessed by measuring malondialdehyde, nitric oxide, and glutathione levels, which the researchers described as indicators of tissue toxicity. The researchers concluded that pulse-modulated RF radiation causes oxidative injury in liver, lung, testis, and heart tissues mediated by lipid peroxidation, increased NOx, and suppression of antioxidant defense.

Exposure Details

SAR
1.2 W/kg
Source/Device
900 MHz
Exposure Duration
20 min/day for three weeks

Exposure Context

This study used 1.2 W/kg for SAR (device absorption):

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextStudy Exposure Level in ContextThis study: 1.2 W/kgExtreme Concern - 0.1 W/kgFCC Limit - 1.6 W/kgEffects observed in the Extreme Concern range (Building Biology)FCC limit is 1 times higher than this level
A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 900 MHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 900 MHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

Study Details

We aimed to investigate whether 900 MHz pulse-modulated radiofrequency (RF) fields induce oxidative damage on lung, heart and liver tissues.

We assessed oxidative damage by investigating lipid peroxidation (malondialdehyde, MDA), nitric oxid...

MDA and NOx levels were increased significantly in liver, lung, testis and heart tissues of the expo...

Results of our study showed that pulse-modulated RF radiation causes oxidative injury in liver, lung, testis and heart tissues mediated by lipid peroxidation, increased level of NOx and suppression of antioxidant defense mechanism

Cite This Study
Esmekaya MA, Ozer C, Seyhan N (2011). 900 MHz pulse-modulated radiofrequency radiation induces oxidative stress on heart, lung, testis and liver tissues Gen Physiol Biophys. 30(1):84-89, 2011.
Show BibTeX
@article{ma_2011_900_mhz_pulsemodulated_radiofrequency_524,
  author = {Esmekaya MA and Ozer C and Seyhan N},
  title = {900 MHz pulse-modulated radiofrequency radiation induces oxidative stress on heart, lung, testis and liver tissues},
  year = {2011},
  
  url = {https://europepmc.org/article/med/21460416},
}
PubMed: 21460416

Cited By (102 papers)

View all 102 citing papers on Semantic Scholar

Quick Questions About This Study

The study used 30 male Wistar albino rats divided into three groups of ten.
Rats were exposed to 900 MHz pulse-modulated RF radiation at a SAR of 1.20 W/kg for 20 minutes per day for three weeks.
Oxidative stress markers were significantly changed in liver, lung, testis, and heart tissues of the exposed group.
No significant difference was observed between the sham and control groups.
Researchers measured malondialdehyde, nitric oxide, and glutathione levels, which they described as indicators of tissue toxicity.