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Oxidative Stress129 citations

Effects of mobile phones on oxidant/antioxidant balance in cornea and lens of rats

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Balci M, Devrim E, Durak I · 2007

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Mobile phone radiation was associated with oxidative stress markers in rat corneal and lens tissues, and vitamin C appeared to help prevent these effects.

Plain English Summary

Summary written for general audiences

Researchers assigned forty female albino Wistar rats to one of four groups to study the effects of mobile phone radiation on oxidant/antioxidant balance in corneal and lens tissues. One group received mobile phone radiation for 4 weeks, a second group received radiation plus a daily oral dose of vitamin C (250 mg/kg), a third group received vitamin C alone, and a fourth group served as a control. In corneal tissue, MDA level and CAT activity significantly increased and SOD activity was significantly decreased in the mobile phone group compared with the control group. In lens tissue, only the MDA level significantly increased in the mobile phone group relative to the control group, while SOD, GSH-Px, and CAT did not differ significantly between groups.

Why This Matters

The study measured malondialdehyde (MDA) levels and activities of superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), and catalase (CAT) in corneal and lens tissues using spectrophotometric methods. The mobile phone group showed significantly higher MDA and CAT activity and lower SOD activity in corneal tissue compared with the control group. The lens showed a more limited response, with only MDA rising significantly and the other enzyme markers showing no significant differences. The researchers suggest that vitamin C can help to prevent the observed effects of mobile telephone radiation on oxidative stress in these tissues.

Exposure Details

SAR
1.2 W/kg
Source/Device
900 MHz
Exposure Duration
4 x 10 min/day, for 4 weeks

Exposure Context

This study used 1.2 W/kg for SAR (device absorption):

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextStudy Exposure Level in ContextThis study: 1.2 W/kgExtreme Concern - 0.1 W/kgFCC Limit - 1.6 W/kgEffects observed in the Extreme Concern range (Building Biology)FCC limit is 1 times higher than this level
A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 900 MHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 900 MHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

Study Details

To investigate the effects of mobile-phone-emitted radiation on the oxidant/antioxidant balance in corneal and lens tissues and to observe any protective effects of vitamin C in this setting.

Forty female albino Wistar rats were assigned to one of four groups containing 10 rats each. One gro...

In corneal tissue, MDA level and CAT activity significantly increased in the mobile phone group comp...

The results of this study suggest that mobile telephone radiation leads to oxidative stress in corneal and lens tissues and that antioxidants such as vitamin C can help to prevent these effects.

Cite This Study
Balci M, Devrim E, Durak I (2007). Effects of mobile phones on oxidant/antioxidant balance in cornea and lens of rats Curr Eye Res. 32(1):21-25, 2007.
Show BibTeX
@article{m_2007_effects_of_mobile_phones_512,
  author = {Balci M and Devrim E and Durak I},
  title = {Effects of mobile phones on oxidant/antioxidant balance in cornea and lens of rats},
  year = {2007},
  doi = {10.1080/02713680601114948},
  url = {https://www.tandfonline.com/doi/abs/10.1080/02713680601114948},
}
DOI: 10.1080/02713680601114948

Cited By (129 papers)

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Quick Questions About This Study

Forty female albino Wistar rats were assigned to one of four groups of 10 rats each, receiving mobile phone radiation, radiation plus vitamin C, vitamin C alone, or standard laboratory care as a control.
In corneal tissue, MDA level and CAT activity significantly increased and SOD activity was significantly decreased in the mobile phone group compared with the control group.
In lens tissue, only the MDA level significantly increased in the mobile phone group, while significant differences were not found between groups in terms of SOD, GSH-Px, or CAT.
The results suggest that antioxidants such as vitamin C can help to prevent the effects of mobile telephone radiation on oxidative stress in corneal and lens tissues.
MDA levels and activities of SOD, GSH-Px, and CAT in corneal and lens tissues were measured with spectrophotometric methods.