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Short-term memory in mice is affected by mobile phone radiation

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Ntzouni MP, Stamatakis A, Stylianopoulou F, Margaritis LH. · 2011

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The 'chronic exposure-I' protocol showed a major effect, suggesting a possible severe interaction of EMF with the consolidation phase of recognition memory processes in mice.

Plain English Summary

Summary written for general audiences

Researchers studied the effects of mobile phone electromagnetic fields on a non-spatial memory task called the Object Recognition Task in mice. Three groups of mice were tested under three different radiation exposure protocols, with a SAR value of 0.22 W/kg. Results revealed a major effect on the "chronic exposure-I" protocol, suggesting a possible severe interaction of EMF with the consolidation phase of recognition memory processes.

Why This Matters

In the first protocol, mice were exposed to mobile phone radiation during the habituation, training, and test sessions of the task, but not during the 10-minute inter-trial interval where memory consolidation takes place. In the second protocol, the same mice were exposed for 17 days for 90 min/per day starting at PND55, with radiation present only during the inter-trial interval phase of the memory test. In the third protocol, mice continued to be exposed daily under the same conditions up to PND86 having received radiation for 31 days. The researchers suggested that the primary EMF target may be the information transfer pathway connecting the entorhinal-parahippocampal regions, which participate in the memory task.

Exposure Details

SAR
0.22 W/kg
Electric Field
17 V/m
Source/Device
1,800 MHz
Exposure Duration
90 min/day for 3 days (acute exposure), 17 days (chronic exposure-I) or 31 days (chronic exposure-II)

Exposure Context

This study used 17 V/m for electric fields:

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextStudy Exposure Level in ContextThis study: 0.22 W/kgExtreme Concern - 0.1 W/kgFCC Limit - 1.6 W/kgEffects observed in the Extreme Concern range (Building Biology)FCC limit is 7 times higher than this level
A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 1.80 GHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 1.80 GHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

Study Details

To study the Short-term memory in mice is affected by mobile phone radiation.

The effects of mobile phone electromagnetic fields (EMFs) were studied on a non-spatial memory task ...

One day later the ORT test was performed without irradiation present in any of the sessions. The ORT...

Cite This Study
Ntzouni MP, Stamatakis A, Stylianopoulou F, Margaritis LH. (2011). Short-term memory in mice is affected by mobile phone radiation Pathophysiology. 18(3):193-199, 2011.
Show BibTeX
@article{mp_2011_shortterm_memory_in_mice_162,
  author = {Ntzouni MP and Stamatakis A and Stylianopoulou F and Margaritis LH.},
  title = {Short-term memory in mice is affected by mobile phone radiation},
  year = {2011},
  
  url = {https://www.sciencedirect.com/science/article/abs/pii/S092846801000060X},
}

Quick Questions About This Study

Researchers tested non-spatial memory using the Object Recognition Task, which requires entorhinal cortex function.
The "chronic exposure-I" protocol showed the major effect, suggesting a possible severe interaction of EMF with the consolidation phase of recognition memory.
Mice were exposed to mobile phone radiation at a SAR value of 0.22 W/kg.
Researchers suggested the primary EMF target may be the information transfer pathway connecting the entorhinal-parahippocampal regions, which participate in the Object Recognition Task.