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The antioxidant effect of Green Tea Mega EGCG against electromagnetic radiation-induced oxidative stress in the hippocampus and striatum of rats

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Ahmed NA, Radwan NM, Aboul Ezz HS, Salama NA · 2017

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EMR exposure disturbed oxidant and antioxidant parameters in rat brain regions, and green tea mega EGCG given during exposure showed more benefit than EGCG given after two months of exposure.

Plain English Summary

Summary written for general audiences

Researchers exposed adult rats to EMR at a frequency of 900 MHz modulated at 217 Hz, with a power density of 0.02 mW/cm2 and SAR of 1.245 W/kg, and measured oxidative stress parameters in the hippocampus and striatum. EMR exposure produced disturbances in oxidant and antioxidant parameters in both brain regions. Green tea mega EGCG given at the beginning of EMR exposure for two and three months had more beneficial effect against EMR-induced oxidative stress than EGCG given after two months of exposure.

Why This Matters

The study divided animals into four groups: EMR-exposed animals, animals treated with green tea mega EGCG after two months of EMR exposure, animals treated with green tea mega EGCG during EMR exposure, and control animals. The study also aimed to evaluate the therapeutic effect of green tea mega EGCG on oxidative stress parameters in animals exposed to EMR both after and during exposure. The researchers suggested that using green tea before a stressor may attenuate the state of oxidative stress and stimulate the antioxidant mechanism of the brain.

Exposure Details

SAR
1.245 W/kg
Power Density
0.02 mW/cm²
Source/Device
900 MHz modulated at 217 Hz
Exposure Duration
2 Months

Exposure Context

This study used 0.02 mW/cm² for radio frequency:

This study used 1.245 W/kg for SAR (device absorption):

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextStudy Exposure Level in ContextThis study: 0.02 mW/cm²Extreme Concern - 1,000 µW/m²FCC Limit - 10M µW/m²Effects observed in the Extreme Concern range (Building Biology)FCC limit is 50 times higher than this level
A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 217 Hz - 900 MHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 217 Hz - 900 MHzPower lines50/60 HzCell phones~1 GHzWiFi2.4 GHz5G mm28 GHzLogarithmic scale

Study Details

The aim of the present study was to investigate the effect of EMR (frequency 900 MHz modulated at 217 Hz, power density 0.02 mW/cm2, SAR 1.245 W/kg) on different oxidative stress parameters in the hippocampus and striatum of adult rats. This study also extends to evaluate the therapeutic effect of green tea mega EGCG on the previous parameters in animals exposed to EMR after and during EMR exposure.

The experimental animals were divided into four groups: EMR-exposed animals, animals treated with gr...

EMR exposure resulted in oxidative stress in the hippocampus and striatum as evident from the distur...

This recommends the use of green tea before any stressor to attenuate the state of oxidative stress and stimulate the antioxidant mechanism of the brain.

Cite This Study
Ahmed NA, Radwan NM, Aboul Ezz HS, Salama NA (2017). The antioxidant effect of Green Tea Mega EGCG against electromagnetic radiation-induced oxidative stress in the hippocampus and striatum of rats Electromagn Biol Med. 2017;36(1):63-73, 2017.
Show BibTeX
@article{na_2017_the_antioxidant_effect_of_504,
  author = {Ahmed NA and Radwan NM and Aboul Ezz HS and Salama NA},
  title = {The antioxidant effect of Green Tea Mega EGCG against electromagnetic radiation-induced oxidative stress in the hippocampus and striatum of rats},
  year = {2017},
  doi = {10.1080/15368378.2016.1194292},
  url = {https://www.tandfonline.com/doi/abs/10.1080/15368378.2016.1194292},
}

Cited By (44 papers)

Quick Questions About This Study

The study used EMR at a frequency of 900 MHz modulated at 217 Hz, with a power density of 0.02 mW/cm2 and a SAR of 1.245 W/kg.
Researchers examined oxidative stress parameters in the hippocampus and striatum of adult rats.
EMR exposure resulted in oxidative stress in the hippocampus and striatum, as shown by disturbances in oxidant and antioxidant parameters.
Green tea mega EGCG given at the beginning of EMR exposure for two and three months had more beneficial effect than when given after two months of exposure.
Animals were divided into four groups: EMR-exposed, treated with EGCG after two months of EMR exposure, treated with EGCG during EMR exposure, and controls.