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Changes in antioxidant capacity of blood due to mutual action of electromagnetic field (1800 MHz) and opioid drug (tramadol) in animal model of persistent inflammatory state.

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Bodera P, Stankiewicz W, Zawada K, Antkowiak B, Paluch M, Kieliszek J, Kalicki B, Bartosiński A, Wawer I. · 2013

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Cell phone radiation at 1800 MHz significantly reduced blood antioxidant capacity in just 15 minutes of exposure.

Plain English Summary

Summary written for general audiences

Researchers exposed rats to cell phone radiation at 1800 MHz (the same frequency used by GSM phones) for 15 minutes and measured changes in their blood's antioxidant capacity. They found that this brief exposure significantly reduced the blood's ability to neutralize harmful free radicals, both in healthy rats and those with inflammation. The study also tested interactions with tramadol (a pain medication) and found the radiation effects were amplified when combined with the drug.

Why This Matters

This study adds to the growing evidence that cell phone radiation can trigger oxidative stress in biological systems, even from relatively brief exposures. The 1800 MHz frequency tested is identical to what millions of people are exposed to daily through GSM cell phones, making these findings directly relevant to human health concerns. What makes this research particularly significant is that it demonstrates measurable biological effects occurred after just 15 minutes of exposure, and that pre-existing inflammation or certain medications may amplify these effects. The reality is that most people carry phones that emit these same frequencies for hours each day, often in direct contact with their bodies. While this was an animal study, the consistent pattern of oxidative stress findings across multiple research teams suggests our cellular antioxidant systems are being challenged by routine RF exposure in ways we're only beginning to understand.

Exposure Information

Specific exposure levels were not quantified in this study. The study examined exposure from: 1800 MHz Duration: 15 minutes

Study Details

The aim of this study is to investigate Changes in antioxidant capacity of blood due to mutual action of electromagnetic field (1800 MHz) and opioid drug (tramadol) in animal model of persistent inflammatory state.

Experiments were performed in healthy rats and in rats with persistent inflammatory state induced by...

Our study revealed that single EMF exposure in 1800 MHz frequency significantly reduced antioxidant ...

The aim of the study was to examine the possible, parallel/combined effects of electromagnetic radiation, artificially induced inflammation and a centrally-acting synthetic opioid analgesic drug, tramadol, (used in the treatment of severe pain) on the antioxidant capacity of blood of rats. The antioxidant capacity of blood of healthy rats was higher than that of rats which received only tramadol and were exposed to electromagnetic fields.

Cite This Study
Bodera P, Stankiewicz W, Zawada K, Antkowiak B, Paluch M, Kieliszek J, Kalicki B, Bartosiński A, Wawer I. (2013). Changes in antioxidant capacity of blood due to mutual action of electromagnetic field (1800 MHz) and opioid drug (tramadol) in animal model of persistent inflammatory state. Pharmacol Rep. 65(2):421-428, 2013.
Show BibTeX
@article{p_2013_changes_in_antioxidant_capacity_1914,
  author = {Bodera P and Stankiewicz W and Zawada K and Antkowiak B and Paluch M and Kieliszek J and Kalicki B and Bartosiński A and Wawer I.},
  title = {Changes in antioxidant capacity of blood due to mutual action of electromagnetic field (1800 MHz) and opioid drug (tramadol) in animal model of persistent inflammatory state.},
  year = {2013},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/23744426/},
}

Quick Questions About This Study

Researchers exposed rats to cell phone radiation at 1800 MHz (the same frequency used by GSM phones) for 15 minutes and measured changes in their blood's antioxidant capacity. They found that this brief exposure significantly reduced the blood's ability to neutralize harmful free radicals, both in healthy rats and those with inflammation. The study also tested interactions with tramadol (a pain medication) and found the radiation effects were amplified when combined with the drug.