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Physiologic effects of electroanesthesia

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Sanford J. Larson, Anthony Sances, Jr. · 1968

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1968 research proved electrical fields can alter brain function and consciousness, establishing the biological basis for EMF health concerns.

Plain English Summary

Summary written for general audiences

This 1968 study by Larson examined how electrical currents affect the nervous system during electroanesthesia, focusing on brain wave activity in visual and auditory regions. The research explored how extremely low frequency electrical fields influence neural transmission and sensory processing. This early work helped establish scientific understanding of how external electrical fields can alter normal brain function.

Why This Matters

This pioneering research from 1968 represents some of the earliest scientific documentation that electrical fields can directly alter brain function. The study examined electroanesthesia, a medical technique that uses electrical currents to induce unconsciousness, providing clear evidence that external electromagnetic fields can interfere with normal neural transmission. What makes this particularly relevant today is that the extremely low frequency fields studied here are similar to those emitted by our electrical grid and many household appliances.

The science demonstrates that if electrical fields can reliably alter consciousness and sensory processing in controlled medical settings, we should take seriously the potential for everyday EMF exposures to affect brain function in subtler ways. While your home's electrical fields are much weaker than those used in electroanesthesia, the principle remains the same: external electromagnetic fields can influence how your nervous system operates.

Figures from the Original Paper

Diagrams extracted from the original research document.

diagramPage 3 - Fig. 1: Recordings from a squirrel monkey evoked by electronic stimulation of the optic tract.
chartPage 4 - Figure 3. Impedance determinations expressed as the percentage of variation from control values at different frequencies and intensities of applied current.
graphPage 5 - Figure 5. Distribution of lever presses by squirrel monkeys as time interval discrimination task was learned. By day 2 the highest percentage of responses was at the end of the 60 second interval.

Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 100 Hz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 100 HzCell phones~1 GHzWiFi2.4 GHz5G mm28 GHzLogarithmic scale

Specific exposure levels were not quantified in this study. Duration: 30 minutes

Study Details

To investigate the mechanism and physiologic effects of electrical anesthesia, particularly focusing on cortical versus subcortical effects.

Squirrel monkeys (Saimiri sciureus) and stump-tail macaque monkeys (Macaca spectosa) were used. Elec...

As the level of the applied currents was raised, the amplitude of the cortical somatosensory potenti...

The findings indicate that evoked somatosensory, visual, and auditory potentials as well as recruiting responses are more profoundly affected by the electroanesthesia currents at cortical than at subcortical levels. The parallel disappearance of responsiveness and of cortical-evoked responses suggests that electroanesthesia is largely a cortical phenomenon. Although the currents appear to act at the cortical level, the mechanism is not clear. Since pulses of relatively high frequency are used for electroanesthesia, it appears likely that synaptic mechanisms may be affected. This explanation is supported by theoretical considerations and by the changes in the observed number of synaptic vesicles near the cleft during the application of currents. Spreading depression does not appear to be a likely explanation for electroanesthesia, since the recovery time for evoked potentials is short and the impedance values do not change significantly. The observations to date have not shown adverse metabolic effects. Arterial pCO2 and pH values do not change appreciably from those determined under very light ether anesthesia. In addition, the free fatty acid concentration, which reflects blood catecholamine levels, is not significantly altered. The stability of the impedance values during electroanesthesia suggests that hypoxia does not occur. Conceivably, the currents used for electrical anesthesia in animals may only affect the response to pain rather than to pain perception. However, the disappearance of cortical recruiting responses and of somatosensory, visual, and auditory potentials suggests that cortical processing of afferent impulses is markedly affected. Animals given electroanesthesia repeatedly and without premedication or supplemental agents do not struggle or attempt to escape when the electrodes are applied, as would be expected if the previous experiences had been unpleasant. The observations reported suggest that electrical anesthesia in animals is reversible and safe. The cerebral cortex appears to be more greatly affected than subcortical structures. However, additional physiologic, morphologic, and chemical studies must be done before the safety of the method can be considered proved.

Cite This Study
Sanford J. Larson, Anthony Sances, Jr. (1968). Physiologic effects of electroanesthesia.
Show BibTeX
@article{physiologic_effects_of_electroanesthesia_g5694,
  author = {Sanford J. Larson and Anthony Sances and Jr.},
  title = {Physiologic effects of electroanesthesia},
  year = {1968},
  
  
}
No DOI on file for this study.

Quick Questions About This Study

Electroanesthesia uses controlled electrical currents to induce unconsciousness during medical procedures. It works by disrupting normal neural transmission in the brain, demonstrating that external electrical fields can directly alter nervous system function and consciousness levels.
Electroanesthesia uses much stronger electrical fields than typical household exposures to reliably induce unconsciousness. However, both involve extremely low frequency fields that can influence neural activity, suggesting even weaker everyday exposures may have subtler biological effects.
The research focused on visual and auditory cortex regions of the brain, measuring how electrical fields affected somatosensory potentials in these areas. This showed that electromagnetic fields could selectively influence different brain regions responsible for processing sensory information.
This early research established the scientific principle that external electrical fields can alter brain function and neural transmission. It provides foundational evidence that electromagnetic fields have biological effects on the nervous system, supporting modern concerns about EMF health impacts.
Yes, this 1968 study demonstrated that electrical fields could influence brain activity in visual and auditory processing regions. The research showed measurable changes in somatosensory potentials, indicating that electromagnetic fields can interfere with how the brain processes sensory information.