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Possible effects of different doses of 2.1 GHz electromagnetic radiation on learning, and hippocampal levels of cholinergic biomarkers in Wistar rats

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Authors not listed · 2021

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Rats exposed to 65 V/m of 2.1 GHz radiation for one week showed impaired performance on memory tasks and reduced hippocampal cholinergic biomarker levels.

Plain English Summary

Summary written for general audiences

Researchers exposed rats to 2.1 GHz radiation at 45 V/m or 65 V/m for one week and compared them to a sham-exposed group. They tested memory using object location and Y-maze tasks. Rats exposed to 65 V/m performed worse on both memory tasks. The same rats had lower hippocampal levels of the cholinergic biomarkers AChE, ChAT, and VAChT.

Why This Matters

The researchers also performed numerical dosimetry simulations and found that the 65 V/m exposure produced high simulated SAR values. They suggested that the stronger effect at 65 V/m might be because the rats' snouts were closest to the antenna. The authors noted this was the first report of dose-dependent effects of short-term 2.1 GHz exposure on behavior and cholinergic biomarkers, and called for further mechanistic studies.

Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 2.1 GHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 2.1 GHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

Specific exposure levels were not quantified in this study.

Cite This Study
Unknown (2021). Possible effects of different doses of 2.1 GHz electromagnetic radiation on learning, and hippocampal levels of cholinergic biomarkers in Wistar rats.
Show BibTeX
@article{possible_effects_of_different_doses_of_21_ghz_electromagnetic_radiation_on_learning_and_hippocampal_levels_of_cholinergic_biomarkers_in_wistar_rats_ce2789,
  author = {Unknown},
  title = {Possible effects of different doses of 2.1 GHz electromagnetic radiation on learning, and hippocampal levels of cholinergic biomarkers in Wistar rats},
  year = {2021},
  doi = {10.1080/15368378.2020.1851251},
  
}

Quick Questions About This Study

Rats were exposed to 2.1 GHz radiation at 45 V/m or 65 V/m for one week, with a sham-exposed control group.
The researchers used object location and Y-maze tasks to test memory.
Rats exposed to 65 V/m showed impaired performance on both object location and Y-maze tasks. They also had significantly lower hippocampal levels of AChE, ChAT, and VAChT compared to the other groups.
They suggested it may be because the rats' snouts were nearest to the antenna, leading to higher simulated SAR values at that dose.